von Gynz-Rekowski M E, Schmehl V, Pinnow R
II. Inneren Abteilung, St.-Hedwig-Krankenhauses, Berlin.
Dtsch Z Verdau Stoffwechselkr. 1988;48(6):292-8.
We examined 21 patients with duodenal ulcer confirmed by endoscopy for disturbances of esophageal function, using manometric techniques and long-term pH measurement. Pathological manometric findings, largely of a mild degree, were obtained in 48 per cent of the patients examined, and a pathological gastro-esophageal reflux was found in 81 per cent, with only 33 per cent suffering from reflux esophagitis as confirmed by endoscopy and/or histological examination. Although duodenal ulcer and disturbed esophageal function often appear simultaneously, a causal connection seems unlikely. Alcohol and nicotine stimulate reflux, with the degree of severity depending on the amount.
我们使用测压技术和长期pH测量法，对21例经内镜检查确诊为十二指肠溃疡的患者进行了食管功能紊乱检查。在接受检查的患者中，48%有主要为轻度的病理性测压结果，81%发现有病理性胃食管反流，经内镜检查和/或组织学检查确诊仅33%患有反流性食管炎。尽管十二指肠溃疡和食管功能紊乱常同时出现，但两者之间似乎不太可能存在因果关系。酒精和尼古丁会刺激反流，严重程度取决于摄入量。
