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感染性胰腺坏死的电视辅助腹膜后清创术的结果分析:单中心经验

An outcome analysis of videoscopic assisted retroperitoneal debridement in infected pancreatic necrosis: a single centre experience.

作者信息

Budkule Dattaraj, Desai Gunjan, Pande Prasad, Narkhede Rajvilas, Wagle Prasad, Varty Paresh

机构信息

Clinic of General Surgery and Surgical Gastroenterology, Lilavati Hospital and Research Centre, Mumbai, India.

出版信息

Turk J Surg. 2019 Sep 23;35(3):214-222. doi: 10.5578/turkjsurg.4289. eCollection 2019 Sep.

DOI:10.5578/turkjsurg.4289
PMID:32550331
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6795228/
Abstract

OBJECTIVES

Infected pancreatic necrosis (IPN) is a dreadful complication of moderately severe and severe acute necrotising pancreatitis (ANP). Videoscopic assisted retroperitoneal debridement (VARD) is a minimally invasive surgical option for predominantly left sided, posterior and laterally located disease in patients not responding to conservative and percutaneous options. This study aimed to present an outcome analysis of VARD in the management of IPN at our tertiary care centre.

MATERIAL AND METHODS

The present retrospective analysis of prospectively entered data included 22 patients diagnosed as ANP with IPN from January 2015 to December 2017. These patients were admitted in the surgical gastroenterology unit of our tertiary care centre. The outcome of these patients managed with VARD was evaluated.

RESULTS

The aetiology of ANP was idiopathic, and gallstones were found in 7 patients each and alcohol in 8. Twelve patients were managed with a single VARD procedure; whereas, 10 required a re-debridement due to suboptimal improvement. Eighteen out of 22 patients survived whereas 4 succumbed to major postoperative bleeding/severe sepsis and multiorgan failure (Mortality 18.2%). Hospital stay after the index procedure was between 6 to 11 weeks.

CONCLUSION

VARD is a safe and effective surgical option for the management of IPN that worsens or fails to respond to conservative and percutaneous drainage options after a minimum of 4 weeks of moderately severe and severe ANP. It decreases postoperative morbidity and mortality and avoids major laparotomy, and hence, it can be considered in a selected group of patients.

摘要

目的

感染性胰腺坏死(IPN)是中度重症和重症急性坏死性胰腺炎(ANP)的一种可怕并发症。电视辅助腹膜后清创术(VARD)是一种微创外科手术选择,适用于主要位于左侧、后方和外侧的疾病,且对保守治疗和经皮治疗无效的患者。本研究旨在对我们三级医疗中心采用VARD治疗IPN的结果进行分析。

材料与方法

本项对前瞻性录入数据的回顾性分析纳入了2015年1月至2017年12月期间诊断为ANP合并IPN的22例患者。这些患者入住我们三级医疗中心的外科胃肠病科。对采用VARD治疗的这些患者的结果进行评估。

结果

ANP的病因是特发性的,7例患者病因是胆结石,8例是酒精。12例患者接受了单次VARD手术;而10例患者因改善不理想需要再次清创。22例患者中有18例存活,4例死于术后大出血/严重脓毒症和多器官功能衰竭(死亡率18.2%)。首次手术后的住院时间为6至11周。

结论

VARD是治疗IPN的一种安全有效的手术选择,对于中度重症和重症ANP至少4周后病情恶化或对保守治疗和经皮引流治疗无效的患者适用。它可降低术后发病率和死亡率,避免大手术,因此,可在特定患者群体中考虑使用。

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