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韦尼克脑病:三例病例的相似与不同之处

Wernicke's Encephalopathy: Similar and Different Aspects of the Three Cases.

作者信息

Emre Ufuk, Erdal Yüksel, Söylemez Cansu, KaragöZ Yeşim, Mahmutoğlu Abdullah Soydan

机构信息

Istanbul Training and Research Hospital, Neurology Department, Istanbul, Turkey.

Istanbul Training and Research Hospital, Radiology Department, Istanbul, Turkey.

出版信息

Noro Psikiyatr Ars. 2019 Aug 16;57(2):165-168. doi: 10.29399/npa.22854. eCollection 2020 Jun.

Abstract

Wernicke encephalopathy is a neurological disorder, clasically characterized by altered consciousness, ophtalmoparesis, and ataxia results from tiamin deficiency. It is frequently associated with chronic alcohol abuse; however, many conditions which lead to thiamine deficiency such as gastric surgery, hyperemesis, parenteral nutrition, malnutrition may also be the cause. WE is a life-threatening condition that requires early diagnosis and rapid initiation of intravenous thiamin therapy. In patients, findings of characteristic examinations may not always be seen; therefore, imaging methods are of great importance. In this article, we aimed to emphasize the similar and different aspects of three WE cases with typical and atypical imaging findings.

摘要

韦尼克脑病是一种神经障碍,典型表现为意识改变、眼球运动障碍和共济失调,由硫胺素缺乏引起。它常与慢性酒精滥用有关;然而,许多导致硫胺素缺乏的情况,如胃部手术、妊娠剧吐、肠外营养、营养不良等也可能是病因。韦尼克脑病是一种危及生命的疾病,需要早期诊断并迅速开始静脉注射硫胺素治疗。在患者中,特征性检查结果并非总能见到;因此,影像学方法非常重要。在本文中,我们旨在强调三例具有典型和非典型影像学表现的韦尼克脑病病例的异同点。

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Wernicke's Encephalopathy: Similar and Different Aspects of the Three Cases.韦尼克脑病:三例病例的相似与不同之处
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本文引用的文献

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Atypical Wernicke's encephalopathy showing involvement of substantia nigra.非典型性韦尼克脑病表现为黑质受累。
J Neuroimaging. 2012 Apr;22(2):204-7. doi: 10.1111/j.1552-6569.2010.00545.x. Epub 2010 Dec 1.
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Atypical MRI findings of Wernicke encephalopathy in alcoholic patients.酒精性患者韦尼克脑病的非典型MRI表现。
AJR Am J Roentgenol. 2010 Nov;195(5):W372-3; author reply W374. doi: 10.2214/AJR.10.4539.
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Neurological complications of prolonged hunger strike.长期绝食的神经并发症。
Eur J Neurol. 2006 Oct;13(10):1089-97. doi: 10.1111/j.1468-1331.2006.01531.x.
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Acute axonal neuropathy and Wernicke's encephalopathy.急性轴索性神经病和韦尼克脑病。
J Neurol. 2006 Nov;253(11):1516-7. doi: 10.1007/s00415-006-0266-5. Epub 2006 Sep 13.

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