Pradhan Chandni, Khadka Simanta, Joshi Purushottam
Mechi Eye Hospital, Birtamod-9, Jhapa, Nepal.
Bharatpur Eye Hospital, Bharatpur-10, Chitwan, Nepal.
Case Rep Ophthalmol Med. 2020 May 29;2020:6023586. doi: 10.1155/2020/6023586. eCollection 2020.
Angle closure glaucoma (ACG) whether primary or secondary lens induced has rare occurrence in cases with retinitis pigmentosa (RP).
Five patients with history of diminished vision, ocular pain, and nyctalopia were clinically evaluated. Four patients had unilateral presentations of circumciliary congestion, corneal edema, and high intraocular pressure (IOP), while one had bilateral presentation, respectively. Anterior chambers were shallow; fundoscopy revealed the features of RP and gonioscopy affirmed closed angles in all the cases. The management strategies were individualized based on the specific ocular condition.
The raised IOP were not well controlled with conventional medical treatment. Neodymium yttrium aluminium garnet laser peripheral iridotomy (LPI) was performed in two patients and in the fellow eye in other two patients as a prophylactic measure. Phacoemulsification surgery with implantation of intraocular lens (IOL) was performed in three patients, whereas phacoemulsification only without IOL and trabeculectomy performed in one patient. Among them, two patients had subluxated lens, where one was managed with capsular tension ring and the other was left aphakic, respectively. However, the vision was not improved significantly in these patients.
RP may be associated with ACG in rare instances. In these patients, angle closure-related high IOP can have a detrimental effect on the pre-existing visual impairment. However, this can be prevented by thorough clinical examination and timely intervention in those susceptible eyes.
闭角型青光眼(ACG),无论是原发性还是继发性晶状体诱导型,在视网膜色素变性(RP)患者中均罕见。
对5例有视力下降、眼痛和夜盲病史的患者进行临床评估。4例患者表现为单侧睫状充血、角膜水肿和高眼压(IOP),1例为双侧表现。前房浅;眼底镜检查显示RP特征,房角镜检查证实所有病例房角关闭。根据具体眼部情况制定个体化治疗策略。
常规药物治疗对升高的IOP控制不佳。2例患者行钕钇铝石榴石激光周边虹膜切开术(LPI),另外2例患者的对侧眼作为预防性措施也进行了LPI。3例患者行白内障超声乳化吸除联合人工晶状体(IOL)植入术,1例患者仅行白内障超声乳化吸除术而未植入IOL并进行了小梁切除术。其中,2例患者晶状体半脱位,1例使用囊袋张力环处理,另1例保持无晶状体状态。然而,这些患者的视力并未显著改善。
RP在罕见情况下可能与ACG相关。在这些患者中,与房角关闭相关的高IOP可能会对已有的视力损害产生不利影响。然而,通过全面的临床检查和对易感眼的及时干预可以预防这种情况。