Taneja M K
Indian Institute of Ear Diseases, E-982 C.R. Park, New Delhi, India.
Indian J Otolaryngol Head Neck Surg. 2020 Jun;72(2):247-250. doi: 10.1007/s12070-020-01815-y. Epub 2020 Feb 13.
To compare the efficacy of platelet rich plasma (PRP) in Tympanoplasty. Comparative study of Tympanoplasty with and without PRP. A total of 82 patients having dry large central perforation underwent type I Tympanoplasty by transcanal route under local anesthesia. Control group underwent surgery without PRP. The study group Tympanoplasty was added with PRP by PRP soaked gel foam placed in middle ear, over the graft and in bony canal along with wetting the temporal fascia by PRP graft. Preoperative and post operative audiometry was done. Result compared. Majority of the patients were of the age group of 20-30 years. Success rate of graft uptake was 85.3% in control group and 95.1% in PRP group. Hearing Improvements in control group was 46.3% and in PRP group was 78.0%. This study confirms addition of PRP in Tympanoplasty enhances the success rate in graft uptake early healing with improvement in hearing.
比较富血小板血浆（PRP）在鼓室成形术中的疗效。有PRP与无PRP鼓室成形术的对比研究。共有82例干性中央大穿孔患者在局部麻醉下经耳道途径接受I型鼓室成形术。对照组手术未使用PRP。研究组在鼓室成形术中通过将PRP浸泡的明胶海绵置于中耳、移植物上方及骨性耳道内，并将PRP浸湿颞肌筋膜移植物来添加PRP。进行术前和术后听力测定并比较结果。大多数患者年龄在20 - 30岁。对照组移植物摄取成功率为85.3%，PRP组为95.1%。对照组听力改善率为46.3%，PRP组为78.0%。本研究证实鼓室成形术中添加PRP可提高移植物摄取成功率，促进早期愈合并改善听力。
