Division of General Thoracic Surgery, Department of Surgery, Shiga University of Medical Science, Shiga, Japan; Division of General Thoracic Surgery, Kusatsu General Hospital, Shiga, Japan.
Division of General Thoracic Surgery, Department of Surgery, Shiga University of Medical Science, Shiga, Japan.
Ann Thorac Surg. 2020 Dec;110(6):e541-e543. doi: 10.1016/j.athoracsur.2020.04.114. Epub 2020 Jun 15.
Dissemination of pseudomyxoma peritonei into the thoracic cavity is rare and carries a poor prognosis. Optimal treatment has not been defined. In our institution, patients have received cytoreductive surgery with hyperthermic intrathoracic chemotherapy, which demonstrated a good prognosis. A 51-year-old woman was referred to our hospital with right intrathoracic dissemination of pseudomyxoma peritonei. We performed parietal and mediastinal pleurectomy and simple resection of all visible tumors on the diaphragm and visceral pleura, followed by hyperthermic intrathoracic chemotherapy with 20 mg mitomycin at 42°C to 43°C. The patient had no evidence of disease progression in the thoracic cavity 1 year after surgery.
腹膜假黏液瘤播散至胸腔较为罕见，且预后不良。目前尚未明确最佳治疗方法。在我院，患者接受细胞减灭术联合高热胸腔内化疗，取得了良好的预后。一名 51 岁女性因右侧胸腔腹膜假黏液瘤播散至我院就诊。我们为其实施壁层和纵隔胸膜切除术，以及对所有可见的膈胸膜和脏层胸膜肿瘤进行单纯切除术，随后在 42°C 至 43°C 下用 20 mg 丝裂霉素行高热胸腔内化疗。术后 1 年，患者胸腔内无疾病进展证据。
