Suppr超能文献

[角膜器官培养在可能感染严重急性呼吸综合征冠状病毒2的供体中的重要性]

[Importance of corneal organ culture in donors with possible SARS-CoV-2 infections].

作者信息

Thaler Sebastian, Schindler Michael, Iftner Thomas, Bartz-Schmidt Karl Ulrich, Bayyoud Tarek

机构信息

Department für Augenheilkunde, Eberhard Karls Universität, Elfriede-Aulhorn-Str. 7, 72076, Tübingen, Deutschland.

Institut für Medizinische Virologie und Epidemiologie, Eberhard Karls Universität, Elfriede-Aulhorn-Str. 6, 72076, Tübingen, Deutschland.

出版信息

Ophthalmologe. 2020 Jul;117(7):622-625. doi: 10.1007/s00347-020-01152-z.

Abstract

The appearance of the novel severe acute respiratory syndrome-coronavirus-2 (SARS-CoV‑2) poses challenges in ophthalmology particularly for eye banks. A valid risk assessment for the removal and processing of donor corneas is difficult due to the lack of data. The risk to infect transplant recipients with SARS-CoV‑2 still appears very unlikely due to the experience with severe acute respiratory syndrome -coronavirus(‑1) (SARS-CoV(‑1)) and Middle East respiratory syndrome-coronavirus (MERS-CoV); however, due to the occurrence of angiotensin-converting enzyme 2 (ACE2) receptors in the cornea an infection of this tissue with SARS-CoV‑2 cannot be completely excluded. Therefore, routine testing of the organ culture medium used for donor corneas for SARS-CoV‑2 prior to transplantation during the coronavirus disease 2019 (COVID‑19) pandemic should be considered.

摘要

新型严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的出现给眼科带来了挑战,尤其是对眼库而言。由于缺乏数据,对捐献角膜的摘取和处理进行有效的风险评估很困难。根据严重急性呼吸综合征冠状病毒(-1)(SARS-CoV(-1))和中东呼吸综合征冠状病毒(MERS-CoV)的经验,将SARS-CoV-2传染给移植受者的风险似乎仍然非常低;然而,由于角膜中存在血管紧张素转换酶2(ACE2)受体,不能完全排除SARS-CoV-2感染该组织的可能性。因此,在2019冠状病毒病(COVID-19)大流行期间,应考虑在移植前对用于捐献角膜的器官培养基进行SARS-CoV-2的常规检测。

相似文献

7
6 The impact of COVID-19 on corneal transplantation in England.6. COVID-19 对英格兰角膜移植的影响。
BMJ Open Ophthalmol. 2022 Nov;7(Suppl 2):A3. doi: 10.1136/bmjophth-2022-EEBA.6.

本文引用的文献

2

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验