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腹腔镜食管裂孔疝修补术中使用补片的手术和临床结果比较。

Surgical and clinical outcomes comparison of mesh usage in laparoscopic hiatal hernia repair.

机构信息

Department of Surgery, University of Nebraska Medical Center, 986245 Nebraska Medical Center, Omaha, NE, 68198-6245, USA.

Center for Advanced Surgical Technology, University of Nebraska Medical Center, 986246 Nebraska Medical Center, Omaha, NE, 68198-6246, USA.

出版信息

Surg Endosc. 2021 Jun;35(6):2724-2730. doi: 10.1007/s00464-020-07703-4. Epub 2020 Jun 16.

Abstract

PURPOSE

Use of absorbable mesh in hiatal hernia (HH) repair has been shown to decrease recurrence rates. Our aim was to compare the efficiency of three meshes in relation to the surgical outcomes of patients undergoing HH repair.

METHODS

A single-institution retrospective review was done for adult patients who underwent HH repair with mesh between 2004 and 2016. Demographics, intra-operative, and cost data were collected. Esophageal symptoms and medication use were assessed pre- and postoperatively. Surgical outcomes were evaluated at 6-, 12-months, and long-term follow-up. Three groups were created based on type of mesh: human tissue matrix (HTM), biosynthetic mesh (BIOS), or porcine tissue matrix (PTM). Comparisons were performed between groups using SPSS v.26.0 and PC SAS v9.4, α = 0.05.

RESULTS

292 patients were included (HTM:N = 162, BIOS:N = 83, PTM:N = 47). Majority were male (60.4%), Caucasian (93.2%), median age, and BMI of 59 years [25-90 years] and 29.19 kg/m [18.9-58.0 kg/m], respectively. 69% had a large HH. Median follow-up time was 27 months [1-166 months]. Overall recurrence rate was 39%, being significantly lower in BIOS at long-term (HTM: 31%, BIOS: 17%, PTM: 19%, p = 0.038). All groups had a significant postoperative improvement of esophageal symptoms, all p < 0.001. 65-70% of the cost difference between the groups was incurred by the cost of mesh alone (HTM: $1072, BIOS: $548, PTM: $1295), with the remainder attributable to the surgery itself.

CONCLUSION

While outcomes of the three mesh groups were similar in our data, there was a significant difference in mesh cost. Surgeon and hospital preference still play a role in choosing the type of mesh used; however, knowledge of the individual mesh cost will help surgeons make better informed decisions.

摘要

目的

在食管裂孔疝(HH)修复中使用可吸收网片已被证明可降低复发率。我们的目的是比较三种网片在接受 HH 修复的患者的手术结果方面的效率。

方法

对 2004 年至 2016 年间接受网片 HH 修复的成年患者进行单中心回顾性研究。收集人口统计学、术中数据和成本数据。评估术前和术后食管症状和药物使用情况。在 6 个月、12 个月和长期随访时评估手术结果。根据网片类型创建了三组:人组织基质(HTM)、合成网片(BIOS)或猪组织基质(PTM)。使用 SPSS v.26.0 和 PC SAS v9.4 对组间进行比较,α=0.05。

结果

共纳入 292 例患者(HTM:N=162,BIOS:N=83,PTM:N=47)。大多数为男性(60.4%),白种人(93.2%),中位年龄和 BMI 分别为 59 岁[25-90 岁]和 29.19kg/m[18.9-58.0kg/m]。69%的患者有大 HH。中位随访时间为 27 个月[1-166 个月]。总体复发率为 39%,长期 BIOS 明显较低(HTM:31%,BIOS:17%,PTM:19%,p=0.038)。所有组的食管症状均有显著改善,均 p<0.001。组间成本差异的 65-70%由网片单独成本引起(HTM:$1072,BIOS:$548,PTM:$1295),其余归因于手术本身。

结论

尽管我们的数据中三组网片的结果相似,但网片成本存在显著差异。外科医生和医院的偏好仍然在选择使用的网片类型方面发挥作用;然而,了解单个网片的成本将帮助外科医生做出更明智的决策。

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