Shandong University of Traditional Chinese Medicine, Jinan 250355, Shandong, China.
Shandong Academy of Traditional Chinese Medicine, Jinan 250014, Shandong, China.
Fitoterapia. 2020 Oct;146:104675. doi: 10.1016/j.fitote.2020.104675. Epub 2020 Jun 17.
Species of Cinnamomum exhibit excellent economic and medicinal value, and have found use in traditional medicine, are consumed as a spice, as well as being cultivated as landscape plants. Investigations into the pharmacological activities of the genus Cinnamomum revealed that it manifested a wide range of pharmacological properties including antimicrobial, antioxidant, anti-inflammatory and analgesic, antitumor, anti-diabetic and anti-obesity, immunoregulation, insecticidal and acaricidal, cardiovascular protective, cytoprotective, as well as neuroprotective properties both in vivo and in vitro. In the past five years, approximately 306 chemical constituents have been separated and identified from the genus Cinnamomum, covering 111 terpenes, 44 phenylpropanoids, 51 lignans, 17 flavonoids, 53 aromatic compounds, 17 aliphatic compounds, four coumarins, two steroids. This article highlights the traditional uses, phytochemistry and pharmacological properties of the few studied taxa of Cinnamomum through searching for the pieces of literature both at home and abroad, which would provide a reference for the pharmaceutical research and clinical application of this genus.
肉桂属植物具有优良的经济和药用价值，在传统医学中被用作药物，被用作香料，也被种植为景观植物。对肉桂属植物的药理学活性的研究表明，它表现出广泛的药理学特性，包括抗菌、抗氧化、抗炎和镇痛、抗肿瘤、抗糖尿病和抗肥胖、免疫调节、杀虫和杀螨、心血管保护、细胞保护以及体内和体外的神经保护特性。在过去的五年中，从肉桂属植物中分离和鉴定了大约 306 种化学成分，涵盖 111 种萜类化合物、44 种苯丙素类化合物、51 种木脂素类化合物、17 种类黄酮类化合物、53 种芳香族化合物、17 种脂肪族化合物、4 种香豆素类化合物、2 种甾体化合物。本文通过国内外文献检索，重点介绍了少数几种经过研究的肉桂属植物的传统用途、植物化学和药理学特性，为该属的药物研究和临床应用提供了参考。
