Institute of Physiology of Komi Science Centre of the Ural Branch of the Russian Academy of Sciences, FRC Komi SC UB RAS, 50 Pervomayskaya str., 167982 Komi Republic, Syktyvkar, Russia.
Institute of Physiology of Komi Science Centre of the Ural Branch of the Russian Academy of Sciences, FRC Komi SC UB RAS, 50 Pervomayskaya str., 167982 Komi Republic, Syktyvkar, Russia.
Fitoterapia. 2020 Oct;146:104676. doi: 10.1016/j.fitote.2020.104676. Epub 2020 Jun 16.
The review outlines the main aspects of the use of pectin polysaccharides in medicine, both as independent medicinal substances and as a material for creating systems for targeted delivery of drugs, as well as for regenerative medicine and biomedical engineering. A number of studies demonstrate that pectin polysaccharides are physiologically active substances with immunomodulating properties, including anti-inflammatory activity, they lower cholesterol and triglyceride in the blood serum, normalize glucose metabolism, bind and remove toxins and radionuclides from the body, regulate work and provide protection of the gastrointestinal tract, have anticarcinogenic and antimetastatic effects.
综述概述了果胶多糖在医学中的主要应用方面，既可以作为独立的药用物质，也可以作为用于靶向药物输送系统的材料，以及用于再生医学和生物医学工程。许多研究表明，果胶多糖是具有免疫调节特性的生理活性物质，包括抗炎活性，它们可以降低血清中的胆固醇和甘油三酯，使葡萄糖代谢正常化，结合并清除体内的毒素和放射性核素，调节和保护胃肠道，具有抗癌和抗转移作用。
