Donaldson L L
Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Leesburg, VA 24061.
Vet Surg. 1988 Jan-Feb;17(1):53-7. doi: 10.1111/j.1532-950x.1988.tb00275.x.
Dobutamine was infused (1.7 micrograms/kg/minute) into 200 anesthetized horses as treatment for hypotension. The horses had been premedicated with xylazine, and anesthesia was induced with guaifenesin and ketamine and maintained with halothane. One hundred fifty-seven horses (79%) responded with an average increase in systolic blood pressure of at least 10 mm Hg within 10 minutes. A cardiac arrhythmia developed in 56 horses (28%) after dobutamine administration: 34 with sinus bradycardia, 18 with atrioventricular block, 2 with premature atrial contractions, and 2 with atrioventricular dissociation. Dobutamine intravenous infusion was effective treatment for hypotension in horses anesthetized with halothane.
将多巴酚丁胺（1.7微克/千克/分钟）输注到200匹麻醉的马中以治疗低血压。这些马已预先用赛拉嗪进行了预处理，并用愈创甘油醚和氯胺酮诱导麻醉，并用氟烷维持麻醉。157匹马（79%）在10分钟内反应良好，收缩压平均至少升高10毫米汞柱。56匹马（28%）在给予多巴酚丁胺后出现心律失常：34例为窦性心动过缓，18例为房室传导阻滞，2例为房性早搏，2例为房室分离。多巴酚丁胺静脉输注是氟烷麻醉马低血压的有效治疗方法。
