Department of Plastic Surgery, Cleveland Clinic, Cleveland Clinic Main Campus, Crile Building, 6th Floor, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
J Endocrinol Invest. 2020 Oct;43(10):1529-1530. doi: 10.1007/s40618-020-01333-2. Epub 2020 Jun 19.
Charles II (1661-1700) was the last King of the Habsburg dynasty. He was physically and mentally disabled and died at just 39 years old. Here, the authors attempt to investigate the correlations between his signs and symptoms and the physical appearance on the painting.
Charles II has been portraited by Juan Carreño de Miranda in a painting that may provide precious information about his premature death.
It has been suggested that inbreeding beside other endocrinological disorders were of the major causes responsible for illness and ultimately his death.
Possible endocrinological diseases have been hypothesized.
查理二世（1661-1700 年）是哈布斯堡王朝的最后一位国王。他身体和精神都有残疾，年仅 39 岁就去世了。在这里，作者试图研究他的症状和体征与画作上的外貌之间的相关性。
胡安·卡雷尼奥·德·米兰达（Juan Carreño de Miranda）曾为查理二世绘制过一幅画像，这幅画像可能提供了有关他早逝的宝贵信息。
有人认为，近亲繁殖以及其他内分泌紊乱是导致他患病并最终死亡的主要原因。
作者推测他可能患有内分泌疾病。
