Novel approach for low-dose pulmonary delivery of hydroxychloroquine in COVID-19.
作者信息
Fassihi Safa C, Nabar Neel R, Fassihi Reza
机构信息
Department of Orthopaedic Surgery, George Washington University, Washington, DC, USA.
Laboratory of Immunoregulation, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
出版信息
Br J Pharmacol. 2020 Nov;177(21):4997-4998. doi: 10.1111/bph.15167. Epub 2020 Jul 13.
Abstract
摘要
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Nat Med. 2020 Jun;26(6):808-809. doi: 10.1038/s41591-020-0888-2.
2
Hydroxychloroquine as an aerosol might markedly reduce and even prevent severe clinical symptoms after SARS-CoV-2 infection.羟氯喹雾化吸入可能显著减少甚至预防 SARS-CoV-2 感染后的严重临床症状。
Med Hypotheses. 2020 Sep;142:109783. doi: 10.1016/j.mehy.2020.109783. Epub 2020 Apr 27.
3
In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).羟氯喹治疗严重急性呼吸综合征冠状病毒 2 （SARS-CoV-2）的体外抗病毒活性和优化剂量设计预测。
Clin Infect Dis. 2020 Jul 28;71(15):732-739. doi: 10.1093/cid/ciaa237.
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