Ciufolini Ignazio, Paolozzi Antonio
Dipartimento di Ingegneria dell'Innovazione, University of Salento, Lecce, Italy.
Centro Fermi, Rome, Italy.
Eur Phys J Plus. 2020;135(6):495. doi: 10.1140/epjp/s13360-020-00488-4. Epub 2020 Jun 15.
We present an improved mathematical analysis of the time evolution of the Covid-19 pandemic in Italy and a statistical error analyses of its evolution, including a Monte Carlo simulation with a very large number of runs to evaluate the uncertainties in its evolution. A previous analysis was based on the assumption that the number of nasopharyngeal swabs would be constant. However, the number of daily swabs is now more than five times what it was when we did our previous analysis. Therefore, here we consider the time evolution of the ratio of the new daily cases to number of swabs, which is more representative of the evolution of the pandemic when the number of swabs is increasing or changing in time. We consider a number of possible distributions representing the evolution of the pandemic in Italy, and we test their prediction capability over a period of up to 6 weeks. The results show that a distribution of the type of Planck black body radiation law provides very good forecasting. The use of different distributions provides an independent possible estimate of the uncertainty. We then consider five possible trajectories for the number of daily swabs and we estimate the potential dates of a substantial reduction in the number of new daily cases. We then estimate the spread in a substantial reduction, below a certain threshold, of the daily cases per swab among the Italian regions. We finally perform a Monte Carlo simulation with 25,000 runs to evaluate a random uncertainty in the prediction of the date of a substantial reduction in the number of diagnosed daily cases per swab.
我们对意大利新冠疫情的时间演变进行了改进的数学分析,并对其演变进行了统计误差分析,包括进行大量运行的蒙特卡洛模拟,以评估其演变过程中的不确定性。之前的分析基于鼻咽拭子数量将保持不变的假设。然而,现在每日拭子数量是我们进行上次分析时的五倍多。因此,在这里我们考虑新增每日病例数与拭子数量之比的时间演变,当拭子数量增加或随时间变化时,这一比值更能代表疫情的演变情况。我们考虑了一些可能代表意大利疫情演变的分布,并在长达6周的时间内测试它们的预测能力。结果表明,普朗克黑体辐射定律类型的分布提供了非常好的预测。使用不同的分布提供了对不确定性的独立可能估计。然后我们考虑了每日拭子数量的五种可能轨迹,并估计了新增每日病例数大幅减少的潜在日期。接着我们估计了意大利各地区每拭子每日病例数大幅减少至低于某个阈值的范围。最后,我们进行了25000次运行的蒙特卡洛模拟,以评估每拭子每日确诊病例数大幅减少日期预测中的随机不确定性。