Clinical Psychoacoustics Lab, 3rd Psychiatry Department, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Clinical Psychoacoustics Lab, 3rd Psychiatry Department, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Psychiatry Res. 2020 Sep;291:113222. doi: 10.1016/j.psychres.2020.113222. Epub 2020 Jun 10.
The present study investigates the presence of Auditory Processing Disorder (APD) in schizophrenia and its association with symptomatology, especially Formal Thought Disorder (FTD). 50 patients with schizophrenia and 25 matched healthy controls completed a battery of three auditory processing tests. Positive and Negative Syndrome Scale (PANSS) and Thought, Language and Communication (TLC) scale were used to assess clinical symptoms. The patient group was divided into two subgroups, according to FTD severity. Auditory processing performance of the control group and the patient group was evaluated. Correlations between auditory processing scores and TLC scores, as well as auditory processing scores and PANSS scores were examined. Most of the patients, especially those with FTD, had auditory deficits that can be classified as APD. Patients showed impaired performance compared to controls in all tests. Total severity and specific factors of FTD, as well as other clinical symptoms and symptom categories were correlated with auditory processing performance. We provided evidence that APD may be present in schizophrenia and that FTD, as well as other clinical symptoms are associated with auditory processing deficits. There are important clinical implications for non-pharmacological interventions and early diagnosis of schizophrenia.
本研究旨在探讨精神分裂症中听觉处理障碍(APD)的存在及其与症状的关系,特别是与形式思维障碍(FTD)的关系。50 名精神分裂症患者和 25 名匹配的健康对照组完成了三项听觉处理测试。阳性和阴性症状量表(PANSS)和思维、语言和沟通(TLC)量表用于评估临床症状。根据 FTD 的严重程度,将患者组分为两个亚组。评估了对照组和患者组的听觉处理表现。检查了听觉处理分数与 TLC 分数之间的相关性,以及听觉处理分数与 PANSS 分数之间的相关性。大多数患者,尤其是那些有 FTD 的患者,存在可归类为 APD 的听觉缺陷。与对照组相比,患者在所有测试中表现出较差的表现。FTD 的总严重程度和特定因素,以及其他临床症状和症状类别与听觉处理表现相关。我们提供了证据表明 APD 可能存在于精神分裂症中,并且 FTD 以及其他临床症状与听觉处理缺陷有关。这对精神分裂症的非药物干预和早期诊断具有重要的临床意义。