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由于听觉感知缺陷与认知障碍之间的相关性对精神分裂症早期诊断和治疗的意义

Implications for Early Diagnosis and Treatment in Schizophrenia Due to Correlation between Auditory Perceptual Deficits and Cognitive Impairment.

作者信息

Moschopoulos Nikolaos, Nimatoudis Ioannis, Kaprinis Stergios, Boutsikos Kosmas, Sidiras Christos, Iliadou Vasiliki

机构信息

Clinical Psychoacoustics Lab, 3rd Psychiatry Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.

2nd Psychiatry Department, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.

出版信息

J Clin Med. 2021 Sep 30;10(19):4557. doi: 10.3390/jcm10194557.

Abstract

It is indicated that auditory perception deficits are present in schizophrenia and related to formal thought disorder. The purpose of the present study was to investigate the association of auditory deficits with cognitive impairment in schizophrenia. An experimental group of 50 schizophrenia patients completed a battery of auditory processing evaluation and a neuropsychological battery of tests. Correlations between neuropsychological battery scores and auditory processing scores were examined. Cognitive impairment was correlated with auditory processing deficits in schizophrenia patients. All neuropsychological test scores were significantly correlated with at least one auditory processing test score. Our findings support the coexistence of auditory processing disorder, severe cognitive impairment, and formal thought disorder in a subgroup of schizophrenia patients. This may have important implications in schizophrenia research, as well as in early diagnosis and nonpharmacological treatment of the disorder.

摘要

研究表明,精神分裂症患者存在听觉感知缺陷,且与形式思维障碍有关。本研究的目的是调查精神分裂症患者听觉缺陷与认知障碍之间的关联。一个由50名精神分裂症患者组成的实验组完成了一系列听觉处理评估和一组神经心理学测试。检查了神经心理学测试分数与听觉处理分数之间的相关性。精神分裂症患者的认知障碍与听觉处理缺陷相关。所有神经心理学测试分数均与至少一项听觉处理测试分数显著相关。我们的研究结果支持在一部分精神分裂症患者中存在听觉处理障碍、严重认知障碍和形式思维障碍。这可能对精神分裂症研究以及该疾病的早期诊断和非药物治疗具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fed6/8509531/b07d3b85df41/jcm-10-04557-g001.jpg

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