Novo Giuseppina, Nugara Cinzia, Fava Antonella, Mantero Antonio, Citro Rodolfo
Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Division of Cardiology University Hospital P. Giaccone, Palermo, Italy.
Neurolesi Center IRCCS "Bonino Pulejo", Messina, Italy.
J Cardiovasc Echogr. 2020 Apr;30(Suppl 1):S4-S10. doi: 10.4103/jcecho.jcecho_2_19. Epub 2020 Apr 10.
Cardiovascular diseases are possible complications of antineoplastic treatment and may lead to premature morbidity and mortality among cancer survivors. A symptom-based follow-up is ineffective, and there are growing evidences that early detection of myocardial damage in patients treated with antineoplastic drugs is the key point to prevent the occurrence of damage and improve the prognosis of these patients. Different techniques have been proposed to monitor cardiac function in oncologic patients such as cardiac imaging (echocardiography, nuclear imaging, and cardiac magnetic resonance) and biomarkers (troponin and natriuretic peptides). The European Association of Cardiovascular Imaging/American Society of Echocardiography consensus document encourages an integrated approach to early detect cardiotoxicity.
心血管疾病是抗肿瘤治疗可能出现的并发症,可能导致癌症幸存者过早发病和死亡。基于症状的随访效果不佳,越来越多的证据表明,在接受抗肿瘤药物治疗的患者中早期发现心肌损伤是预防损伤发生和改善这些患者预后的关键。已经提出了不同的技术来监测肿瘤患者的心脏功能,如心脏成像(超声心动图、核成像和心脏磁共振)和生物标志物(肌钙蛋白和利钠肽)。欧洲心血管影像协会/美国超声心动图学会的共识文件鼓励采用综合方法早期检测心脏毒性。