Olesen F
J R Coll Gen Pract. 1988 Aug;38(313):356-9.
Despite widespread cervical smear testing 500-600 cases of cancer of the cervix are still diagnosed each year in Denmark, with over 200 deaths. The distribution of the different stages of cancer among 420 women who were diagnosed during 1983 was correlated with the number of previous cervical smears, whether done purely for screening reasons or for minor gynaecological problems. Of the women with cancer 56% had never been screened, and among these 42% were diagnosed at stage 1; 19% had been screened once; 61% of them at stage 1. The remainder (25%) had been screened at least twice, and 81% of them were diagnosed at stage 1. Among the patients who had been screened at least twice, with the last screening not more than three or five years ago, about 90% were diagnosed at stage 1 and the rest at stage 2.The introduction of cervical smear testing will thus mean a considerably better stage distribution among cases which develop invasive cancer of the cervix, and both case fatality and mortality rates will be reduced by organized programmes, which have better participation rates than disorganized use of cervical smears.
尽管丹麦广泛开展了宫颈涂片检查，但每年仍有500 - 600例宫颈癌被确诊，其中超过200人死亡。对1983年确诊的420名女性患者不同癌症阶段的分布情况，与之前宫颈涂片检查的次数进行了关联分析，这些检查是单纯出于筛查目的，还是因轻微妇科问题而进行的。患有癌症的女性中，56%从未接受过筛查，其中42%在1期被诊断出癌症；19%接受过一次筛查，其中61%在1期被诊断出癌症。其余（25%）至少接受过两次筛查，其中81%在1期被诊断出癌症。在至少接受过两次筛查且最后一次筛查不超过三或五年前的患者中，约90%在1期被诊断出癌症，其余在2期。因此，宫颈涂片检查的引入将意味着在发生宫颈浸润癌的病例中，病例分期分布会显著改善，通过有组织的项目，病例死亡率和死亡率都将降低，这些项目的参与率比无组织地使用宫颈涂片更高。
