School of Biosciences and Veterinary Medicine, Università degli Studi di Camerino, Camerino (MC), Italy.
Laboratory of Protistology and Biology Education, Department of E.C.H.T. Università degli Studi di Macerata, Macerata, Italy.
Eur J Protistol. 2020 Aug;75:125720. doi: 10.1016/j.ejop.2020.125720. Epub 2020 Jun 4.
For hundreds of years, mankind has benefited from the natural metabolic processes of microorganisms to obtain basic products such as fermented foods and alcoholic beverages. More recently, microorganisms have been exploited for the production of antibiotics, vitamins and enzymes to be used in medicine and chemical industries. Additionally, several modern drugs, including those for cancer therapy, are natural products or their derivatives. Protists are a still underexplored source of natural products potentially of interest for biotechnological and biomedical applications. This paper focuses on some examples of bioactive molecules from protists and associated bacteria and their possible use in biotechnology.
数百年来，人类受益于微生物的自然代谢过程，从中获得了发酵食品和酒精饮料等基本产品。最近，人们还利用微生物生产抗生素、维生素和酶，用于医药和化学工业。此外，一些现代药物，包括癌症治疗药物，都是天然产物或其衍生物。原生动物仍然是一个尚未充分开发的天然产物来源，对于生物技术和生物医学应用具有潜在的重要性。本文重点介绍了一些来自原生动物及其相关细菌的生物活性分子的例子，以及它们在生物技术中的可能用途。
