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硬膜外脊髓电刺激治疗严重心绞痛

Epidural spinal electrical stimulation in severe angina pectoris.

作者信息

Mannheimer C, Augustinsson L E, Carlsson C A, Manhem K, Wilhelmsson C

机构信息

Department of Medicine, Ostra Hospital, Gothenburg, Sweden.

出版信息

Br Heart J. 1988 Jan;59(1):56-61. doi: 10.1136/hrt.59.1.56.

Abstract

The short term effects of epidural spinal electrical stimulation were studied in 10 patients with angina pectoris of New York Heart Association functional class III or IV. The antianginal pharmacological treatment given at entry to the study was regarded as optimal and was not changed during the study. The effects of epidural spinal electrical stimulation were measured by repeated bicycle ergometer tests. Treatment with epidural spinal electrical stimulation increased the patients' working capacity, decreased ST segment depression, increased time to angina, and reduced the recovery time. The observed effects did not seem to be correlated with any changes in myocardial oxygen demand during epidural spinal electrical stimulation and were additional to the benefits of the pharmacological treatment.

摘要

对10例纽约心脏协会功能分级为III级或IV级的心绞痛患者研究了硬膜外脊髓电刺激的短期效果。研究开始时给予的抗心绞痛药物治疗被视为最佳治疗方案,且在研究期间未改变。通过重复的自行车测力计测试来测量硬膜外脊髓电刺激的效果。硬膜外脊髓电刺激治疗增加了患者的工作能力,减少了ST段压低,延长了心绞痛发作时间,并缩短了恢复时间。观察到的效果似乎与硬膜外脊髓电刺激期间心肌需氧量的任何变化无关,并且是药物治疗益处之外的额外效果。

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