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局部热疗对大鼠坐骨神经运动功能的影响。

Effects of local hyperthermia on the motor function of the rat sciatic nerve.

作者信息

Wondergem J, Haveman J, Rusman V, Sminia P, Van Dijk J D

机构信息

Department of Radiotherapy, University of Amsterdam, The Netherlands.

出版信息

Int J Radiat Biol Relat Stud Phys Chem Med. 1988 Mar;53(3):429-38. doi: 10.1080/09553008814552561.

DOI:10.1080/09553008814552561
PMID:3257955
Abstract

The effect of local heat treatment of the sciatic nerve was assessed using the toe-spreading test, which mainly assesses the motor function of the sciatic nerve. A 5 mm long segment of the nerve was heated at temperatures from 42.0 to 45.0 degrees C in vivo using a brass thermode. Hyperthermia led to a decrease in spreading of the toes. Recovery from functional loss took place in all cases, and this recovery was completed in 4 weeks. A 50 per cent functional loss in 50 per cent of the treated animals was observed after 58, 32 and 12 min of heating at 43.0, 44.0 and 45.0 degrees C respectively.

摘要

使用趾展试验评估坐骨神经局部热处理的效果,该试验主要评估坐骨神经的运动功能。在体内使用黄铜热电极将5毫米长的神经段加热至42.0至45.0摄氏度。热疗导致趾展减少。所有病例的功能丧失均有恢复,且在4周内恢复完成。分别在43.0、44.0和45.0摄氏度下加热58、32和12分钟后,观察到50%的受试动物出现50%的功能丧失。

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