Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands,
Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Oncol Res Treat. 2020;43(9):405-413. doi: 10.1159/000508312. Epub 2020 Jun 24.
Experimental studies have shown that palliative care team (PCT) involvement can improve quality of life (QoL) and symptom burden of patients with advanced cancer. It is unclear to what extent this effect is sustained in daily practice of hospital care.
This observational study aims to investigate the effect of PCT consultation on QoL and symptom burden of hospitalized patients with advanced cancer in daily practice.
After admission to 1 of 9 participating hospitals, patients with advanced cancer for whom the attending physician answered "no" to the Surprise Question were invited to complete a questionnaire, including the EORTC QLQ-C15-PAL, at 6 points in time, until 3 months after admission. Outcomes were compared between patients who received PCT consultation and patients who did not, taking into account differences in baseline characteristics.
A total of 164 patients consented to participate, of whom 32 received PCT consultation. Of these patients, 108 were able to complete a questionnaire at day 14, of whom 19 after receiving PCT consultation. After adjusting for baseline differences, EORTC QLQ-C15-PAL scores for pain, appetite, and emotional functioning at day 14 were more favorable for patients who received a PCT consultation.
PCT consultation decreased patients' symptom burden and tends to have a positive effect on QoL of hospitalized patients with advanced cancer, even if the PCT is consulted late in the patient's disease trajectory.
实验研究表明,姑息治疗团队(PCT)的参与可以改善晚期癌症患者的生活质量(QoL)和症状负担。尚不清楚这种影响在医院日常护理实践中能持续到何种程度。
本观察性研究旨在调查姑息治疗咨询对晚期癌症住院患者在日常实践中的生活质量和症状负担的影响。
在 9 家参与医院之一入院后,对于主治医生对“惊喜问题”回答为“否”的晚期癌症患者,邀请他们在 6 个时间点填写问卷,包括 EORTC QLQ-C15-PAL,直至入院后 3 个月。考虑到基线特征的差异,比较了接受姑息治疗咨询和未接受姑息治疗咨询的患者的结局。
共有 164 名患者同意参与,其中 32 名患者接受了姑息治疗咨询。这些患者中有 108 名在第 14 天完成了问卷,其中 19 名在接受姑息治疗咨询后完成了问卷。在调整了基线差异后,第 14 天接受姑息治疗咨询的患者的 EORTC QLQ-C15-PAL 评分在疼痛、食欲和情绪功能方面更有利。
姑息治疗咨询减轻了患者的症状负担,并倾向于对晚期癌症住院患者的生活质量产生积极影响,即使姑息治疗在患者疾病轨迹的晚期才被咨询。