Krymskaia L G, Gromykhina N Iu, Kozlov V A
Biull Eksp Biol Med. 1988 Mar;105(3):311-3.
The influence of macrophage secretion product on the functional activity of the adrenal glands has been studied in mice. It has been shown that intravenously injected interleukin-1 caused dose-dependent increase in corticosterone content in the blood plasma. The hormonal response of the adrenal glands to interleukin-1 injection was abolished by the inhibition of prostaglandin synthesis. The results obtained indicate that interleukin-1 stimulates the functional activity of the adrenal glands, with the effect mediated by prostaglandins.
在小鼠中研究了巨噬细胞分泌产物对肾上腺功能活性的影响。结果表明，静脉注射白细胞介素-1会导致血浆中皮质酮含量呈剂量依赖性增加。肾上腺对白细胞介素-1注射的激素反应可通过抑制前列腺素合成而消除。所得结果表明，白细胞介素-1刺激肾上腺的功能活性，其作用由前列腺素介导。
