Winter Amelia R, Camargo Macias Kathlyn, Kim Sun, Sami Naveed, Weinstein David
Internal Medicine, University of Central Florida College of Medicine, Orlando, USA.
Dermatology, University of Central Florida College of Medicine, Orlando, USA.
Cureus. 2020 May 22;12(5):e8235. doi: 10.7759/cureus.8235.
Raynaud's phenomenon (RP) is a relatively common syndrome occurring alone or in combination with autoimmune and inflammatory diseases. It is characterized by pain and ulceration due to vasospasm in response to cold and stress, most often affecting the digits. Although pharmacologic treatment for this condition exists, it is not always efficacious. Our case series demonstrates the use of abobotulinum toxin A in the treatment of RP. We report the cases of four patients who received injections of abobotulinum toxin A to treat their mild to severe RP symptoms. They experienced clinical improvement for up to one year after treatment.
雷诺现象（RP）是一种相对常见的综合征，可单独出现或与自身免疫性疾病和炎症性疾病合并出现。其特征是因寒冷和压力引发血管痉挛导致疼痛和溃疡，最常影响手指。尽管针对这种病症有药物治疗方法，但并非总是有效。我们的病例系列展示了阿柏西普肉毒毒素A在治疗RP中的应用。我们报告了4例接受阿柏西普肉毒毒素A注射以治疗其轻至重度RP症状的患者病例。他们在治疗后临床改善持续了长达一年的时间。
