Yamanaka Ryoken, Sekino Yohei, Babasaki Takashi, Kitano Hiroyuki, Ikeda Kenichiro, Goto Keisuke, Hieda Keisuke, Inoue Shogo, Hayashi Tetsutaro, Teishima Jun, Aikata Hiroshi, Chayama Kazuaki, Sentani Kazuhiro, Yasui Wataru, Matsubara Akio
Department of Urology, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551 Japan.
Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Int Cancer Conf J. 2020 Mar 25;9(3):141-145. doi: 10.1007/s13691-020-00409-3. eCollection 2020 Jul.
We report a rare case of renal metastasis from primary hepatocellular carcinoma (HCC). A mass in the right kidney of a 71-year-old man was detected by follow-up computed tomography (CT) for HCC. He was diagnosed as having primary HCC 18 years ago and had undergone partial hepatectomy, transarterial chemoembolization, and pulmonary segmentectomy for primary HCC and its metastasis over 10 years. Eight years after this, follow-up CT revealed a right kidney mass, and laboratory testing showed an elevated level of protein induced by vitamin K absence II (PIVKA-II). We performed laparoscopic radical nephrectomy for the right kidney mass. Histopathology revealed renal metastasis from primary HCC. To date, only a small number of cases of renal metastasis from HCC have been reported.
我们报告了一例罕见的原发性肝细胞癌（HCC）肾转移病例。一名71岁男性因HCC接受随访计算机断层扫描（CT）时，发现右肾有一个肿块。他18年前被诊断为原发性HCC，10多年来因原发性HCC及其转移接受了部分肝切除术、经动脉化疗栓塞术和肺段切除术。在此之后8年，随访CT显示右肾有肿块，实验室检查显示维生素K缺乏诱导蛋白II（PIVKA-II）水平升高。我们对右肾肿块进行了腹腔镜根治性肾切除术。组织病理学显示为原发性HCC肾转移。迄今为止，仅有少数HCC肾转移病例的报道。
