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植物源生物活性物质:关键健康益处和当前的纳米系统作为提高其生物利用度的策略。

Plant-food-derived bioactives: Key health benefits and current nanosystems as a strategy to enhance their bioavailability.

机构信息

Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam, Iran.

LEPABE - Dep. of Chemical Engineering, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, s/n, 4200-465 Porto, Portugal.

出版信息

Cell Mol Biol (Noisy-le-grand). 2020 Jun 25;66(4):232-242.

PMID:32583797
Abstract

Natural products interest is gradually increasing worldwide. Plant-food-derived bioactives have a long history of use as a good source of ingredients for valuable medical usages. Plant-based foods consist of micro and macronutrients, and bioactive components, with health-promoting benefits. The handling of complex mixtures of plants has been methodically switched by therapies using a single isolated substance. The delivery of bioactive molecules in nanosystems is enhancing their bioavailability, it is much safer and cost-effective. However, there are many challenges in combining bioactive substances in nanocarrier materials. A discussion related with nanocarriers will be done in this review.

摘要

天然产物的研究兴趣正在全球范围内逐渐增加。植物源性生物活性物质作为有价值的医疗用途的成分来源,具有悠久的使用历史。植物性食物含有微量和常量营养素以及生物活性成分,对健康有促进作用。复杂的植物混合物的处理方法已经逐渐被单一分离物质的疗法所取代。将生物活性分子递送到纳米系统中可以提高它们的生物利用度,而且更安全、更具成本效益。然而,将生物活性物质结合到纳米载体材料中存在许多挑战。本文综述将讨论与纳米载体相关的内容。

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