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生物素化铂(II)金属笼用于靶向癌症治疗学。

Biotinylated platinum(ii) metallacage towards targeted cancer theranostics.

机构信息

State Key Laboratory for Mechanical Behavior of Materials, Shaanxi International Research Center for Soft Matter, School of Materials Science and Engineering, Xi'an Jiaotong University, Xi'an 710049, P. R. China.

School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, P. R. China.

出版信息

Chem Commun (Camb). 2020 Jul 28;56(60):8460-8463. doi: 10.1039/d0cc03824e.

Abstract

A biotinylated metallacage was prepared via metal-coordination-driven self-assembly, combining fluorescence, anti-cancer and targeted properties into a single entity. The metallacage was successfully employed for targeted cell imaging and therapy, offering a platform for cancer theranostics.

摘要

通过金属配位驱动的自组装制备了一种生物素化的金属笼,将荧光、抗癌和靶向特性结合到一个单一实体中。该金属笼成功地用于靶向细胞成像和治疗,为癌症治疗提供了一个平台。

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