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Femoral neck fracture detection in X-ray images using deep learning and genetic algorithm approaches.

作者信息

Beyaz Salih, Açıcı Koray, Sümer Emre

机构信息

Başkent Üniversitesi Adana Turgut Noyan Eğitim ve Araştırma Merkezi Ortopedi ve Travmatoloji Kliniği, 01240 Yüreğir, Adana, Türkiye.

出版信息

Jt Dis Relat Surg. 2020;31(2):175-183. doi: 10.5606/ehc.2020.72163. Epub 2020 Mar 26.


DOI:10.5606/ehc.2020.72163
PMID:32584712
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7489171/
Abstract

OBJECTIVES: This study aims to detect frontal pelvic radiograph femoral neck fracture using deep learning techniques. PATIENTS AND METHODS: This retrospective study was conducted between January 2013 and January 2018. A total of 234 frontal pelvic X-ray images collected from 65 patients (32 males, 33 females; mean age 74.9 years; range, 33 to 89 years) were augmented to 2106 images to achieve a satisfactory dataset. A total of 1,341 images were fractured femoral necks while 765 were non-fractured ones. The proposed convolutional neural network (CNN) architecture contained five blocks, each containing a convolutional layer, batch normalization layer, rectified linear unit, and maximum pooling layer. After the last block, a dropout layer existed with a probability of 0.5. The last three layers of the architecture were a fully connected layer of two classes, a softmax layer and a classification layer that computes cross entropy loss. The training process was terminated after 50 epochs and an Adam Optimizer was used. Learning rate was dropped by a factor of 0.5 on every five epochs. To reduce overfitting, regularization term was added to the weights of the loss function. The training process was repeated for pixel sizes 50x50, 100x100, 200x200, and 400x400. The genetic algorithm (GA) approach was employed to optimize the hyperparameters of the CNN architecture and to minimize the error after testing the model created by the CNN architecture in the training phase. RESULTS: Performance in terms of sensitivity, specificity, accuracy, F1 score, and Cohen's kappa coefficient were evaluated using five- fold cross validation tests. Best performance was obtained when cropped images were rescaled to 50x50 pixels. The kappa metric showed more reliable classifier performance when 50x50 pixels image size was used to feed the CNN. The classifier performance was more reliable according to other image sizes. Sensitivity and specificity rates were computed to be 83% and 73%, respectively. With the inclusion of the GA, this rate increased by 1.6%. The detection rate of fractured bones was found to be 83%. A kappa coefficient of 55% was obtained, indicating an acceptable agreement. CONCLUSION: This experimental study utilized deep learning techniques in the detection of bone fractures in radiography. Although the dataset was unbalanced, the results can be considered promising. It was observed that use of smaller image size decreases computational cost and provides better results according to evaluation metrics.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7612/7489171/6512c25cc904/JDRS-2020-31-2-175-183-F7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7612/7489171/fba29360bc1c/JDRS-2020-31-2-175-183-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7612/7489171/7fba659569d0/JDRS-2020-31-2-175-183-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7612/7489171/4a5a1f7d7bd4/JDRS-2020-31-2-175-183-F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7612/7489171/9c4d14e57123/JDRS-2020-31-2-175-183-F4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7612/7489171/e30114d98a1b/JDRS-2020-31-2-175-183-F5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7612/7489171/aeef57e4d641/JDRS-2020-31-2-175-183-F6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7612/7489171/6512c25cc904/JDRS-2020-31-2-175-183-F7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7612/7489171/fba29360bc1c/JDRS-2020-31-2-175-183-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7612/7489171/7fba659569d0/JDRS-2020-31-2-175-183-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7612/7489171/4a5a1f7d7bd4/JDRS-2020-31-2-175-183-F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7612/7489171/9c4d14e57123/JDRS-2020-31-2-175-183-F4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7612/7489171/e30114d98a1b/JDRS-2020-31-2-175-183-F5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7612/7489171/aeef57e4d641/JDRS-2020-31-2-175-183-F6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7612/7489171/6512c25cc904/JDRS-2020-31-2-175-183-F7.jpg

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引用本文的文献

[1]
Detection and classification of femoral neck fractures from plain pelvic X-rays using deep learning and machine learning methods.

Ulus Travma Acil Cerrahi Derg. 2025-8

[2]
Artificial intelligence in orthopedics: fundamentals, current applications, and future perspectives.

Mil Med Res. 2025-8-4

[3]
Diagnostic Performance of ChatGPT-4o in Detecting Hip Fractures on Pelvic X-rays.

Cureus. 2025-6-24

[4]
Accuracy of artificial intelligence in prediction of osteoporotic fractures in comparison with dual-energy X-ray absorptiometry and the Fracture Risk Assessment Tool: A systematic review.

World J Orthop. 2025-4-18

[5]
Accuracy of artificial intelligence in detecting tumor bone metastases: a systematic review and meta-analysis.

BMC Cancer. 2025-2-18

[6]
Artificial Intelligence-Guided Assessment of Femoral Neck Fractures in Radiographs: A Systematic Review and Multilevel Meta-Analysis.

Orthop Surg. 2025-5

[7]
The Use of Artificial Intelligence for Orthopedic Surgical Backlogs Such as the One Following the COVID-19 Pandemic: A Narrative Review.

JB JS Open Access. 2024-9-19

[8]
Artificial intelligence in musculoskeletal imaging: realistic clinical applications in the next decade.

Skeletal Radiol. 2024-9

[9]
Machine learning model based on radiomics features for AO/OTA classification of pelvic fractures on pelvic radiographs.

PLoS One. 2024

[10]
Proximal femur fracture detection on plain radiography via feature pyramid networks.

Sci Rep. 2024-5-27

本文引用的文献

[1]
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Inf Sci (N Y). 2019-7

[2]
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Proc Mach Learn Res. 2019-6

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What is the importance of canal-to-diaphysis ratio on osteoporosis-related hip fractures?

Eklem Hastalik Cerrahisi. 2019-12

[4]
User-interfaces layout optimization using eye-tracking, mouse movements and genetic algorithms.

Appl Ergon. 2019-3-22

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Med Image Anal. 2019-5

[6]
Application of a deep learning algorithm for detection and visualization of hip fractures on plain pelvic radiographs.

Eur Radiol. 2019-4-1

[7]
Deep learning and SURF for automated classification and detection of calcaneus fractures in CT images.

Comput Methods Programs Biomed. 2019-2-12

[8]
There is an association between sarcopenia, osteoporosis, and the risk of hip fracture.

Eklem Hastalik Cerrahisi. 2019-4

[9]
Can distal radius or vertebra fractures due to low-energy trauma be a harbinger of a hip fracture?

Eklem Hastalik Cerrahisi. 2018-8

[10]
Hip fracture trends in the United States, 2002 to 2015.

Osteoporos Int. 2017-12-27

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