Yang Zhi, Jiang Song, Zhang Yiqiong, Chen Yuan, Tan Yaxin, Su Hong, Xiong Ying, Li Qiongyan, He Li
Department of Dermatology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
J Cosmet Dermatol. 2021 Feb;20(2):481-490. doi: 10.1111/jocd.13568. Epub 2020 Dec 18.
This study is to evaluate the clinical efficacy and safety of a "double-layer" mode of super pulse fractional CO laser and a combined treatment of pinprick therapy with fractional CO laser for the treatment of atrophic acne scars.
A split-face and self-contrast method was applied. A total of 20 patients with atrophic acne scars randomly received the above mentioned therapy on the left or right side of the cheek for 3 times with an interval of 3 months. ECCA scores, IVA scores, patients' satisfaction, VAS scores, and adverse reactions were evaluated.
Atrophic acne scars on both sides of the cheek were improved obviously. The ECCA scores showed a significant decrease, while IVA scores significantly increased. Compared with the super pulse fractional CO laser group, the decrease of ECCA scores, the increase of IVA scores, and the patients' satisfaction were significantly higher and improvement on V-shaped and U-shaped acne scars was significantly better in the combined treatment group. No patients had severe adverse reactions such as blister, infection, or hypertrophic scars.
Super pulse fractional CO laser and pinprick treatment combined with fractional CO laser are both safe and effective therapy for the treatment of atrophic acne scars.
本研究旨在评估超脉冲分数二氧化碳激光“双层”模式及针刺疗法联合分数二氧化碳激光治疗萎缩性痤疮瘢痕的临床疗效及安全性。
采用自身对照的半脸研究方法。共20例萎缩性痤疮瘢痕患者，随机在脸颊左侧或右侧接受上述治疗3次，每次间隔3个月。评估ECCA评分、IVA评分、患者满意度、视觉模拟评分（VAS）及不良反应。
脸颊两侧的萎缩性痤疮瘢痕均明显改善。ECCA评分显著降低，而IVA评分显著升高。与超脉冲分数二氧化碳激光组相比，联合治疗组ECCA评分的降低、IVA评分的升高及患者满意度均显著更高，对V形和U形痤疮瘢痕的改善也明显更好。无患者出现水疱、感染或增生性瘢痕等严重不良反应。
超脉冲分数二氧化碳激光及针刺联合分数二氧化碳激光治疗萎缩性痤疮瘢痕均安全有效。
