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薰衣草精油对伤口愈合的影响:当前证据综述。

The Effects of Lavender Essential Oil on Wound Healing: A Review of the Current Evidence.

机构信息

College of Medicine, University of Nebraska Medical Center, Omaha, NE, USA.

Department of Dermatology, College of Medicine, University of Nebraska Medical Center, Omaha, NE, USA.

出版信息

J Altern Complement Med. 2020 Aug;26(8):680-690. doi: 10.1089/acm.2019.0286. Epub 2020 Jun 24.

Abstract

The commercialization of essential oils has expanded their presence in the United States, and emerging studies demonstrate that they may have a place in Western medicine. One oil with a significant body of evidence is lavender essential oil, which may have benefits in wound healing. This review aims to present the scientific literature on therapeutic lavender essential oil with the goal of expanding the current repertoire of cost-effective wound healing options available to physicians and patients. A review was conducted according to PRISMA guidelines in PubMed, Cochrane Library, and Embase from June 2018 through March 2019 to identify articles related to lavender essential oil in the context of wound healing. This search yielded 36 unique studies, 20 of which remained after screening. This review utilizes human clinical trials ( = 7), animal trials ( = 5), studies ( = 2), and previously conducted reviews ( = 6). Overall, these studies demonstrated a faster rate of wound healing, increased expression of collagen, and enhanced activity of proteins involved in the tissue remodeling process in wounds treated with lavender essential oil. The current body of literature suggests a potential therapeutic benefit of lavender essential oil in wound healing. However, standardization of the chemical composition and additional high-quality human clinical trials are needed to further evaluate the safety and efficacy of lavender essential oil in clinical practice.

摘要

精油的商业化已经使其在美国得到广泛应用,并且新兴研究表明,它们在西方医学中可能有一席之地。一种具有大量证据的油是薰衣草精油,它可能对伤口愈合有益。 本综述旨在介绍有关治疗性薰衣草精油的科学文献,以期扩大医生和患者可获得的具有成本效益的伤口愈合方法的现有范围。 根据 PRISMA 指南,在 2018 年 6 月至 2019 年 3 月期间,在 PubMed、Cochrane 图书馆和 Embase 上进行了检索,以确定与伤口愈合背景下的薰衣草精油相关的文章。 该搜索产生了 36 项独特的研究,经过筛选后仍有 20 项研究。本综述利用了人体临床试验( = 7)、动物试验( = 5)、 研究( = 2)和之前进行的综述( = 6)。总体而言,这些研究表明,用薰衣草精油治疗的伤口愈合速度更快,胶原蛋白表达增加,参与组织重塑过程的蛋白质活性增强。 目前的文献表明,薰衣草精油在伤口愈合方面具有潜在的治疗益处。然而,需要对其化学成分进行标准化,并进行更多高质量的人体临床试验,以进一步评估薰衣草精油在临床实践中的安全性和疗效。

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