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衰老与草药干预:机制洞察与治疗潜力

Aging and Herbal Interventions: Mechanistic Insights and Therapeutic Potential.

作者信息

Suvedi Divyesh, Kumar Anand, Kalia Sonika, Kumar Arun, Koul Sapna, James Abija, Kumar Deepak, Nagraik Rupak, Gulilat Henok

机构信息

Faculty of Applied Sciences and Biotechnology, Shoolini University, Solan, Himachal Pradesh, India.

Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan, Himachal Pradesh, India.

出版信息

J Cosmet Dermatol. 2025 Jul;24(7):e70335. doi: 10.1111/jocd.70335.

Abstract

BACKGROUND

Skin aging is a multifactorial process influenced by an individual's genetic predisposition, lifestyle choices, and environmental factors. This process leads to epidermal thinning, a reduction in collagen and elastin levels, and a decrease in skin suppleness. While aging cannot be entirely prevented, its effects can be mitigated through the application of appropriate skincare products.

AIM

This review examines the potential of natural herbal extracts in anti-aging skincare formulations, focusing on their bioactivity and safety, which aligns with current consumer trends favoring natural, organic, and eco-friendly products.

METHODS

A systematic literature review was performed with the help of PubMed and ScienceDirect to thoroughly examine articles between 2000 and 2025. The review made use of key phrases including "skin aging," "herbal extracts," and "anti-aging cosmetics."

RESULTS

Bioactive compounds such as polyphenols, flavonoids, and essential oils, present in plants, confer multiple benefits for the skin, including moisturizing properties, barrier repair agents, antioxidants, sunscreens, and anti-inflammatory effects. These compounds also protect and rejuvenate the skin through distinct anti-aging mechanisms.

CONCLUSION

The use of herbal extracts in combination with nano-formulations enhances the efficacy of skincare regimens while improving stability. The integration of plant-based resources, when combined with a balanced diet and a healthy lifestyle, can significantly enhance holistic and effective anti-aging skincare.

摘要

背景

皮肤老化是一个多因素过程,受个体遗传易感性、生活方式选择和环境因素影响。这个过程会导致表皮变薄、胶原蛋白和弹性蛋白水平降低以及皮肤柔韧性下降。虽然衰老无法完全预防,但通过使用合适的护肤品可以减轻其影响。

目的

本综述探讨天然草药提取物在抗衰老护肤品配方中的潜力,重点关注其生物活性和安全性,这与当前消费者青睐天然、有机和环保产品的趋势一致。

方法

借助PubMed和ScienceDirect进行了系统的文献综述,以全面研究2000年至2025年间的文章。该综述使用了包括“皮肤老化”、“草药提取物”和“抗衰老化妆品”等关键词。

结果

植物中存在的多酚、黄酮类化合物和精油等生物活性化合物对皮肤有多种益处,包括保湿特性、屏障修复剂、抗氧化剂、防晒剂和抗炎作用。这些化合物还通过独特的抗衰老机制保护皮肤并使其恢复活力。

结论

将草药提取物与纳米制剂结合使用可提高护肤方案的功效,同时提高稳定性。将植物资源与均衡饮食和健康生活方式相结合,可显著增强整体有效的抗衰老护肤效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49d5/12287899/3e6b87758429/JOCD-24-e70335-g005.jpg

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