[Modifications in the urinary excretion of gamma-carboxyglutamic acid induced by vitamin K].
作者信息
Werlen D, Robert D, Leclerq M, Guelpa G, Pfister C E
机构信息
Service de médecine, Hôpital de la Providence, Neuchâtel.
出版信息
Schweiz Med Wochenschr. 1988 Feb 13;118(6):203-5.
PMID:3259010
Abstract
To evaluate urinary GLA excretion, a marker of vitamin K metabolism, the effect of an oral calcium load was studied in 8 volunteers under three conditions: (1) after 1.5 g elementary calcium (calcium carbonate), (2) after 1.5 g calcium (Ossopan, a preparation containing 1 mg osteocalcin per g) and (3) after 1.5 g calcium but with pretreatment of 10 mg vitamin K1 orally for 3 days. No differences in blood calcium, osteocalcin concentration of calciuria were observed. However, GLA excretion was significantly higher with Ossopan or after pretreatment with vitamin K1.
摘要
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引用本文的文献
1
Dietary induced subclinical vitamin K deficiency in normal human subjects.正常人体受试者中饮食诱导的亚临床维生素K缺乏症。
J Clin Invest. 1993 Apr;91(4):1761-8. doi: 10.1172/JCI116386.
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