Department of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou, 215123, China.
Children's Hospital of Soochow University, Suzhou, 215025, China.
Environ Health Prev Med. 2020 Jun 26;25(1):25. doi: 10.1186/s12199-020-00862-9.
Emerging evidence implicates excess weight as a potential risk factor for hearing loss. However, this association remained inconclusive. Therefore, we aimed to systematically and quantitatively review the published observational study on the association between body mass index (BMI) or waist circumference (WC) and hearing loss.
The odds ratios (ORs) or relative risks (RRs) with their 95% confidence intervals (CIs) were pooled under a random-effects model. Fourteen observational studies were eligible for the inclusion in the final analysis.
In the meta-analysis of cross-sectional studies, the ORs for prevalent hearing loss were 1.10 (95% CI 0.88, 1.38) underweight, 1.14 (95% CI 0.99, 1.32) for overweight, OR 1.40 (95% CI 1.14, 1.72) for obesity, 1.14 (95% CI 1.04, 1.24) for each 5 kg/m increase in BMI, and 1.22 (95% CO 0.88. 1.68) for higher WC. In the meta-analysis of longitudinal studies, the RRs were 0.96 (95% CI 0.52, 1.79) for underweight, 1.15 (95% CI 1.04, 1.27) for overweight, 1.38 (95% CI 1.07, 1.79) for obesity, 1.15 (95% CI 1.01, 1.30) for each 5 kg/m increase in BMI, and 1.11 (95% CI 1.01, 1.22) for higher WC.
In summary, our findings add weight to the evidence that elevated BMI and higher WC may be positively associated with the risk of hearing loss.
新出现的证据表明，超重可能是听力损失的一个潜在危险因素。然而，这种关联仍不确定。因此，我们旨在系统地、定量地综述已发表的关于体重指数（BMI）或腰围（WC）与听力损失之间关系的观察性研究。
采用随机效应模型汇总比值比（OR）或相对风险（RR）及其 95%置信区间（CI）。共有 14 项观察性研究符合纳入最终分析的标准。
在横断面研究的荟萃分析中，体重不足的 OR 值为 1.10（95%CI 0.88，1.38），超重的 OR 值为 1.14（95%CI 0.99，1.32），肥胖的 OR 值为 1.40（95%CI 1.14，1.72），BMI 每增加 5kg/m，OR 值为 1.14（95%CI 1.04，1.24），WC 较高的 OR 值为 1.22（95%CO 0.88. 1.68）。在纵向研究的荟萃分析中，体重不足的 RR 值为 0.96（95%CI 0.52，1.79），超重的 RR 值为 1.15（95%CI 1.04，1.27），肥胖的 RR 值为 1.38（95%CI 1.07，1.79），BMI 每增加 5kg/m，RR 值为 1.15（95%CI 1.01，1.30），WC 较高的 RR 值为 1.11（95%CI 1.01，1.22）。
总之，我们的研究结果为 BMI 升高和 WC 升高与听力损失风险之间可能存在正相关关系提供了更多证据。
