AILI - Associazione Italiana Latto-Intolleranti Onlus, Lucca, Italy.
Dietetics and Clinical Nutrition Laboratory, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
J Transl Med. 2020 Jun 26;18(1):260. doi: 10.1186/s12967-020-02429-2.
Worldwide, 70% of the adult population has limited expression of lactase enzyme with a wide variation among different regions and countries. Lactase deficiency may lead to lactose intolerance (LI). Depending both on the amount of lactose ingested and on the lactase activity, people who suffer from lactose malabsorption might experience numerous gastrointestinal and extra-intestinal symptoms and manifestations. Treatment of LI mainly consists of reducing or eliminating lactose from the diet until the symptoms disappear as well as supplementing lactase, and inducing colon microbiome adaptation by probiotics. Cow's milk is one of the major source of calcium and several other vitamins and minerals. Thus, a complete exclusion of dairy products may favor the development of bone diseases such as osteopenia and osteoporosis. Therefore, the dietetic approach has a crucial role in the management of LI patients. Additionally, the use of lactose and milk-derived products in non-dairy products (e.g., baked goods, breakfast cereals, drinks, and processed meat) has become widespread in the modern industry (the so-called "hidden lactose"). In this regard, a strict adherence to the lactose-free diet becomes challenging for LI patients, forced to continuous check of all products and food labels. In fact, lactose-free product labeling is still controversial. Considering that nowadays a specific cut-off value establishing "lactose-free" labeling policy is lacking and that there is no universal law regulating the production and commercialization of "delactosed" products, identification of specific safe and suitable products with a well-recognized lactose-free logo might help consumers. This narrative review aims to identify the dietary management for lactose intolerant people, avoiding symptoms and nutrients deficiencies, helped by the use of specific labelling to guide them to choose the safer product on the market.
在全球范围内,70%的成年人乳糖酶表达有限,不同地区和国家的差异很大。乳糖酶缺乏可能导致乳糖不耐受(LI)。根据摄入的乳糖量和乳糖酶活性的不同,乳糖吸收不良的人可能会出现许多胃肠道和肠外症状和表现。LI 的治疗主要包括减少或消除饮食中的乳糖,直到症状消失,以及补充乳糖酶,并通过益生菌诱导结肠微生物组适应。牛奶是钙和其他几种维生素和矿物质的主要来源之一。因此,完全排除乳制品可能有利于骨质疏松症等骨骼疾病的发展。因此,饮食方法在 LI 患者的管理中起着至关重要的作用。此外,乳糖和牛奶衍生产品在非乳制品(如烘焙食品、早餐麦片、饮料和加工肉类)中的使用在现代工业中已经变得非常普遍(所谓的“隐藏乳糖”)。在这方面,LI 患者严格遵循无乳糖饮食变得具有挑战性,他们被迫持续检查所有产品和食品标签。事实上,无乳糖产品标签仍然存在争议。考虑到目前缺乏确定“无乳糖”标签政策的特定截止值,并且没有普遍的法律来规范“去乳糖”产品的生产和商业化,因此识别具有公认无乳糖标志的特定安全和合适产品可能有助于消费者。本叙述性评论旨在确定乳糖不耐受人群的饮食管理方法,避免出现症状和营养缺乏,并通过使用特定标签来指导他们选择市场上更安全的产品。