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A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models.

作者信息

Loontiens Siebe, Vanhauwaert Suzanne, Depestel Lisa, Dewyn Givani, Van Loocke Wouter, Moore Finola E, Garcia Elaine G, Batchelor Lance, Borga Chiara, Squiban Barbara, Malone-Perez Megan, Volders Pieter-Jan, Olexiouk Volodimir, Van Vlierberghe Pieter, Langenau David M, Frazer J Kimble, Durinck Kaat, Speleman Frank

机构信息

Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.

Cancer Research Institute Ghent (CRIG), Ghent, Belgium.

出版信息

Leukemia. 2020 Dec;34(12):3398-3403. doi: 10.1038/s41375-020-0938-2. Epub 2020 Jun 26.

DOI:10.1038/s41375-020-0938-2
PMID:32591643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7906429/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9568/7906429/3d9370a4a152/nihms-1667347-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9568/7906429/5b07a1a5b31e/nihms-1667347-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9568/7906429/3d9370a4a152/nihms-1667347-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9568/7906429/5b07a1a5b31e/nihms-1667347-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9568/7906429/3d9370a4a152/nihms-1667347-f0002.jpg

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Blood Adv. 2019 Aug 13;3(15):2355-2367. doi: 10.1182/bloodadvances.2019000391.
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Loss Enhances HSC Self-Renewal Driving Tumor Initiation and Leukemia Stem Cell Activity in T-ALL.
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Mutations in Hematologic Malignancies.血液系统恶性肿瘤中的突变
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