A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia through polyA+ and total RNA sequencing.
作者信息
Verboom Karen, Van Loocke Wouter, Volders Pieter-Jan, Decaesteker Bieke, Cobos Francisco Avila, Bornschein Simon, de Bock Charles E, Atak Zeynep Kalender, Clappier Emmanuelle, Aerts Stein, Cools Jan, Soulier Jean, Taghon Tom, Van Vlierberghe Pieter, Vandesompele Jo, Speleman Frank, Durinck Kaat
机构信息
Center for Medical Genetics, Ghent University, Belgium.
Cancer Research Institute Ghent, Belgium.
出版信息
Haematologica. 2018 Dec;103(12):e585-e589. doi: 10.3324/haematol.2018.190587. Epub 2018 Jun 28.
Abstract
摘要
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Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations.儿童T细胞急性淋巴细胞白血病的基因组特征揭示了新的复发性驱动突变。
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Long non-coding RNAs in normal and malignant hematopoiesis.正常和恶性造血过程中的长链非编码RNA
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Melanoma addiction to the long non-coding RNA SAMMSON.黑色素瘤对长链非编码 RNA SAMMSON 的成瘾。
Nature. 2016 Mar 24;531(7595):518-22. doi: 10.1038/nature17161.
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Long non-coding RNA profiling of human lymphoid progenitor cells reveals transcriptional divergence of B cell and T cell lineages.人类淋巴祖细胞的长链非编码RNA分析揭示了B细胞和T细胞谱系的转录差异。
Nat Immunol. 2015 Dec;16(12):1282-91. doi: 10.1038/ni.3299. Epub 2015 Oct 26.
8
Characterization of the genome-wide TLX1 binding profile in T-cell acute lymphoblastic leukemia.T 细胞急性淋巴细胞白血病中 TLX1 全基因组结合谱的特征分析。
Leukemia. 2015 Dec;29(12):2317-27. doi: 10.1038/leu.2015.162. Epub 2015 Jun 25.
9
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia.T细胞急性淋巴细胞白血病中Notch驱动的长链非编码RNA库
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10
Selective inhibition of tumor oncogenes by disruption of super-enhancers.通过破坏超级增强子选择性抑制肿瘤癌基因。
Cell. 2013 Apr 11;153(2):320-34. doi: 10.1016/j.cell.2013.03.036.
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