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用于肾脏疾病研究的组学技术。

Omics technologies for kidney disease research.

机构信息

Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Key Laboratory of Nephrology, National Health Commission and Guangdong Province, Guangzhou, China.

出版信息

Anat Rec (Hoboken). 2020 Oct;303(10):2729-2742. doi: 10.1002/ar.24413. Epub 2020 Jun 26.

Abstract

Omics-based technologies in the areas of genomics, transcriptomics, and proteomics are revolutionizing research into many types of human and experimental disease. This review focuses on the potential of omics technologies to identify pathogenic mechanisms and biomarkers of disease in order to improve the diagnosis, prognosis, monitoring, and treatment of kidney disease.

摘要

基于组学的技术,包括基因组学、转录组学和蛋白质组学,正在彻底改变对多种人类疾病和实验性疾病的研究。本综述重点讨论了组学技术在识别疾病的发病机制和生物标志物方面的潜力,以改善肾脏疾病的诊断、预后、监测和治疗。

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