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中国合肥的白细胞介素 6 与 COVID-19 患者严重程度的关系。

Interleukin-6 and severity of COVID-19 patients in Hefei, China.

机构信息

Department of Infectious Diseases, The First Affiliated Hospital, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, China.

Department of Dermatology, The First Affiliated Hospital, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, China.

出版信息

Med Mal Infect. 2020 Oct;50(7):629-631. doi: 10.1016/j.medmal.2020.06.005. Epub 2020 Jun 25.

DOI:10.1016/j.medmal.2020.06.005
PMID:32593746
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7316053/
Abstract

• Twenty-four out of 75 patients developed into severe condition in the course of the infection. • The prominent laboratory abnormalities of COVID patients were lymphopenia, elevated C-reactive protein (CRP) and lactate dehydrogenase (LDH). • Elevated interleukin 6 (IL-6) correlated with decrease of LYM%, CD4 and CD8 T cell counts, and increase of CRP, LDH and Procalcitonin (PCT) levels.

摘要

• 在感染过程中,75 例患者中有 24 例发展为重症。

• COVID 患者的突出实验室异常包括淋巴细胞减少、C 反应蛋白(CRP)和乳酸脱氢酶(LDH)升高。

• 白细胞介素 6(IL-6)升高与 LYM%、CD4 和 CD8 T 细胞计数减少,以及 CRP、LDH 和降钙素原(PCT)水平升高相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bbf/7316053/05b56d1bad8d/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bbf/7316053/05b56d1bad8d/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bbf/7316053/05b56d1bad8d/gr1_lrg.jpg

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[A pathological report of three COVID-19 cases by minimal invasive autopsies].[三例新冠病毒病病例微创尸检病理报告]
Zhonghua Bing Li Xue Za Zhi. 2020 May 8;49(5):411-417. doi: 10.3760/cma.j.cn112151-20200312-00193.
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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.《武汉 2019 年新型冠状病毒感染的肺炎 138 例住院患者临床特征分析》
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一种新型冠状病毒引发的肺炎疫情,该病毒可能来源于蝙蝠。
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