中国合肥的白细胞介素 6 与 COVID-19 患者严重程度的关系。
Interleukin-6 and severity of COVID-19 patients in Hefei, China.
机构信息
Department of Infectious Diseases, The First Affiliated Hospital, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, China.
Department of Dermatology, The First Affiliated Hospital, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, China.
出版信息
Med Mal Infect. 2020 Oct;50(7):629-631. doi: 10.1016/j.medmal.2020.06.005. Epub 2020 Jun 25.
• Twenty-four out of 75 patients developed into severe condition in the course of the infection. • The prominent laboratory abnormalities of COVID patients were lymphopenia, elevated C-reactive protein (CRP) and lactate dehydrogenase (LDH). • Elevated interleukin 6 (IL-6) correlated with decrease of LYM%, CD4 and CD8 T cell counts, and increase of CRP, LDH and Procalcitonin (PCT) levels.
• 在感染过程中，75 例患者中有 24 例发展为重症。
• COVID 患者的突出实验室异常包括淋巴细胞减少、C 反应蛋白（CRP）和乳酸脱氢酶（LDH）升高。
• 白细胞介素 6（IL-6）升高与 LYM%、CD4 和 CD8 T 细胞计数减少，以及 CRP、LDH 和降钙素原（PCT）水平升高相关。
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