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射频消融治疗带内置冷却灌注电极的被膜下病变:离体研究。

Radiofrequency ablation of subcapsular lesions with internally cooled perfusion electrode: ex vivo study.

机构信息

Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

出版信息

Minim Invasive Ther Allied Technol. 2022 Feb;31(2):216-222. doi: 10.1080/13645706.2020.1783686. Epub 2020 Jun 28.

DOI:10.1080/13645706.2020.1783686
PMID:32594850
Abstract

PURPOSE

To compare the efficiency of an internally cooled perfusion (ICP) electrode and an internally cooled (IC) electrode for radiofrequency ablation (RFA) of subscapular lesions.

MATERIAL AND METHODS

Using 200 W generator and ICP electrode (group A,  = 10) or 15 gauge or 17 gauge IC electrode (group B,  = 10 and group C,  = 10), RFA was applied to the bovine liver for 12 min. Each electrode was inserted at a 3 cm depth into the liver block, and the proximal end of the active exposure portion of each electrode was located at a capsule of the liver block. During RFA, normal saline was pumped through the side hole of the ICP electrode into the tissue at an injection rate of 0.5 mL/min.

RESULTS

The ICP electrode achieved larger capsular ablative area and ablative volume than the IC electrode: 7.29 ± 1.59 cm and 44.56 ± 10.08 cm in group A; 4.36 ± 1.29cm and 30.15 ± 5.97 cm in group B; and 3.57 ± 0.99cm and 24.52 ± 4.21 cm in group C ( < .05), respectively. Mean impedance of ICP RFA was lower than IC RFA: 41.5 ± 3.75Ω in group A; 52.4 ± 5.64Ω in group B; and 58.1 ± 10.98Ω in group C ( < .05).

CONCLUSION

RFA using the ICP electrode more efficiently created a larger capsular ablative area and ablative volume of ablation than IC RFA for subcapsular lesions. The results were obtained in an liver model without tumor simulation inside.

摘要

目的

比较内部冷却灌注(ICP)电极和内部冷却(IC)电极用于射频消融(RFA)治疗肩胛下病变的效率。

材料和方法

使用 200W 发生器和 ICP 电极(A 组,n=10)或 15 号或 17 号 IC 电极(B 组,n=10 和 C 组,n=10),将 RFA 应用于牛肝 12 分钟。每个电极以 3cm 的深度插入肝块,每个电极的近端位于肝块的胶囊内。在 RFA 期间,生理盐水通过 ICP 电极的侧孔以 0.5ml/min 的注射速度泵入组织。

结果

ICP 电极比 IC 电极实现了更大的胶囊消融面积和消融体积:A 组为 7.29±1.59cm 和 44.56±10.08cm;B 组为 4.36±1.29cm 和 30.15±5.97cm;C 组为 3.57±0.99cm 和 24.52±4.21cm( < .05)。ICP RFA 的平均阻抗低于 IC RFA:A 组为 41.5±3.75Ω;B 组为 52.4±5.64Ω;C 组为 58.1±10.98Ω( < .05)。

结论

在没有肿瘤模拟的肝模型中,与 IC RFA 相比,使用 ICP 电极进行 RFA 更有效地创建了更大的胶囊消融面积和消融体积,用于治疗囊下病变。

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