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[抗原给药后过敏患者血清中白细胞迁移抑制因子的检测]

[Detection of a factor suppressing leukocyte migration in the sera of allergy patients following antigen administration].

作者信息

Gorbach A D, Novikov D K, Gorbach I N

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1977 Apr(4):106-10.

PMID:325958
Abstract

The effect on donor leukocyte migration of serum obtained from the patients with tuberculosis of the lungs, chronic pneumonia and healthy persons was studied after subcutaneous or intradermal injection of the microbial antigen (PPD, streptococcus and staphylococcus antigen). A factor inhibiting donor leukocyte migration appeared in the blood serum of sensitized individuals after the antigen injection. This factor proved to be localized in the serum fraction III obtained after the gel-filtration of sephadex G-200, and is sorbed by leukocytes.

摘要

在皮下或皮内注射微生物抗原(结核菌素纯蛋白衍生物、链球菌和葡萄球菌抗原)后,研究了从肺结核、慢性肺炎患者及健康人获取的血清对供体白细胞迁移的影响。抗原注射后,致敏个体的血清中出现了一种抑制供体白细胞迁移的因子。该因子被证明定位于经葡聚糖G - 200凝胶过滤后获得的血清组分III中,并且可被白细胞吸附。

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