Zeng Lingda, Chang Yincheng, Wu Yukun, Yang Jinpeng, Xu Jiang-Fei, Zhang Xi
Key Lab of Organic Optoelectronics and Molecular Engineering, Department of Chemistry, Tsinghua University, Beijing 100084, China.
Sci Adv. 2020 Jun 19;6(25):eaba7524. doi: 10.1126/sciadv.aba7524. eCollection 2020 Jun.
The corrosions caused by sulfate-reducing bacteria (SRB) are serious problems in petroleum exploitation and transportation, which can lead to safety problems, environmental pollutions, and economic losses. Here, a charge-reversal surfactant antibiotic material -dodecyl-1-carboxylic acid-1-cyclohexenyl-2-carboxamide (C12N-DCA) is designed and synthesized. C12N-DCA is a negatively charged surfactant, which cannot be adsorbed by soil and rock in a large amount. Therefore, it can reach the "lesion location", with enough concentration. After being hydrolyzed and charge reversed under the acceleration of HS produced by SRB, C12N-DCA becomes a positively charged surfactant dodecane ammonium salt to kill SRB. Through a simulating experiment, it is found that C12N-DCA can reach the SRB inhibition ratio of almost 100%, and it can reduce iron corrosion by 88%. Such an antibiotic material or its homologs may be added to the chemical flooding fluids, killing SRB during petroleum exploitation and reducing the SRB-induced corrosion in the petroleum exploitation and transportation.
硫酸盐还原菌（SRB）引起的腐蚀是石油开采和运输中的严重问题，会导致安全问题、环境污染和经济损失。在此，设计并合成了一种电荷反转表面活性剂抗菌材料——十二烷基-1-羧酸-1-环己烯基-2-羧酰胺（C12N-DCA）。C12N-DCA是一种带负电荷的表面活性剂，不会大量被土壤和岩石吸附。因此，它能够以足够的浓度到达“病变部位”。在SRB产生的HS加速作用下水解并电荷反转后，C12N-DCA变成带正电荷的表面活性剂十二烷基铵盐以杀死SRB。通过模拟实验发现，C12N-DCA对SRB的抑制率几乎可达100%，并且能使铁腐蚀降低88%。这种抗菌材料或其同系物可添加到化学驱油液中，在石油开采过程中杀死SRB，并减少石油开采和运输中由SRB引起的腐蚀。
