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中国浙江省孕妇样本中轻度至中度碘缺乏和盐碘浓度。

Mild-to-moderate iodine deficiency in a sample of pregnant women and salt iodine concentration from Zhejiang province, China.

机构信息

School of Public Health, Xinxiang Medical University, Xinxiang, 453003, People's Republic of China.

School of Public Health, Zhengzhou University, Science Road 100, Zhengzhou, 450001, People's Republic of China.

出版信息

Environ Geochem Health. 2020 Nov;42(11):3811-3818. doi: 10.1007/s10653-020-00640-0. Epub 2020 Jun 28.

DOI:10.1007/s10653-020-00640-0
PMID:32596780
Abstract

Since 2011, Zhejiang province has eliminated iodine deficiency disorders (IDD) in its populations. Following this achievement, a new revised iodine concentration in iodised salt was implemented in Zhejiang in 2012. However, the re-emergence of iodine deficiency has been reported in pregnant women. Therefore, the aim of this study was to assess household salt iodine concentration and iodine status of pregnant women in Zhejiang province, China. We conducted a cross-sectional study between April 2018 and August 2018 in Quzhou, Zhejiang province. Pregnant women aged ≥ 18 years who did not have a history of thyroid disease were recruited into the study. They were asked to complete socio-demographic questionnaires including a food frequency questionnaire (FFQ). In addition, a spot urine sample and a household table salt sample were also provided by each participant. A total of 625 pregnant women agreed to participate. The overall median urinary iodine concentration (UIC) was 130 µg/L, indicating mild-to-moderate iodine deficiency in pregnant women. The coverage of iodised salt was 85.2%, and of these, the rate of adequately iodised salt was 98.1%. In conclusion, our results confirmed the re-emergence of iodine deficiency in pregnant women as reported by other studies conducted in Zhejiang province. Therefore, urgent public health actions are needed to improve iodine status of pregnant women in order to prevent the adverse consequences of IDD on the neurodevelopment of foetus.

摘要

自 2011 年以来,浙江省已消除了人群中的碘缺乏症(IDD)。在这一成就之后,2012 年浙江省实施了新的修订碘盐浓度。然而,据报道孕妇中碘缺乏症再次出现。因此,本研究旨在评估中国浙江省孕妇家庭盐碘浓度和碘状况。我们于 2018 年 4 月至 8 月在浙江省衢州市进行了一项横断面研究。招募了年龄≥18 岁且无甲状腺疾病史的孕妇参加研究。他们被要求完成社会人口学问卷,包括食物频率问卷(FFQ)。此外,每位参与者还提供了一份尿样和一份家庭食用盐样。共有 625 名孕妇同意参加。总体尿碘中位数(UIC)为 130µg/L,表明孕妇存在轻度至中度碘缺乏。碘盐覆盖率为 85.2%,其中适量碘盐的比例为 98.1%。总之,我们的结果证实了其他在浙江省进行的研究报告的孕妇碘缺乏症的再次出现。因此,需要采取紧急公共卫生行动来改善孕妇的碘状况,以防止碘缺乏症对胎儿神经发育的不良后果。

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