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对各种哺乳动物甲状腺滤泡旁细胞的免疫细胞化学研究。

Immunocytochemical studies on parafollicular cells of various mammals.

作者信息

Zabel M, Schäfer H, Surdyk J, Biela-Jacek I

机构信息

Department of Histology and Embryology, Academy of Medicine, Poznań, Poland.

出版信息

Acta Anat (Basel). 1988;131(3):222-6. doi: 10.1159/000146518.

DOI:10.1159/000146518
PMID:3259783
Abstract

Using specific antisera, calcitonin, calcitonin gene-related peptide (CGRP), somatostatin as well as neuron-specific enolase, chromogranin, secretory peptide I and calbindin (vitamin D-dependent calcium-binding protein) were looked for in parafollicular cells of rats, Syrian hamsters, Mongolian gerbils, mice, guinea pigs, rabbits and pigs. Calcitonin and CGRP were most invariably present in various species. Somatostatin was absent in mice and Mongolian gerbils and present in variable amounts in the remaining species. Neuron-specific enolase could not be detected in rabbits, while in the pigs and the Mongolian gerbils it could be demonstrated only in some parafollicular cells. Calbindin was present exclusively in parafollicular cells of guinea pigs. Chromogranin and secretory protein-I were present only in some animal species.

摘要

使用特异性抗血清,在大鼠、叙利亚仓鼠、蒙古沙鼠、小鼠、豚鼠、兔子和猪的滤泡旁细胞中寻找降钙素、降钙素基因相关肽(CGRP)、生长抑素以及神经元特异性烯醇化酶、嗜铬粒蛋白、分泌肽I和钙结合蛋白(维生素D依赖性钙结合蛋白)。降钙素和CGRP在各种物种中最常出现。生长抑素在小鼠和蒙古沙鼠中不存在,在其余物种中含量不一。兔子中未检测到神经元特异性烯醇化酶,而在猪和蒙古沙鼠中,仅在一些滤泡旁细胞中可检测到。钙结合蛋白仅存在于豚鼠的滤泡旁细胞中。嗜铬粒蛋白和分泌蛋白I仅在某些动物物种中存在。

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Immunocytochemical studies on parafollicular cells of various mammals.对各种哺乳动物甲状腺滤泡旁细胞的免疫细胞化学研究。
Acta Anat (Basel). 1988;131(3):222-6. doi: 10.1159/000146518.
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