Institute of Field and Vegetable Crops Novi Sad, Maksima Gorkog 30, 21000 Novi Sad, Serbia.
Department of Pharmacy, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, Novi Sad 21000, Serbia.
Molecules. 2020 Jun 24;25(12):2898. doi: 10.3390/molecules25122898.
is a plant with high bioactive potential. It contains marrubiin, a labdane diterpene that is characteristic for this genus, as well as a complex mixture of phenolic compounds. According to numerous studies, acts as a good antioxidant agent, and due to this, it could potentially be useful in treatments of cancer, diabetes mellitus, and liver diseases. In addition, its anti-inflammatory, wound-healing, antihypertensive, hypolipidemic, and sedative potential are discussed. Apart from that, its antimicrobial activity, especially against Gram+ bacteria, fungi, herpes simplex virus, and parasites such as , , and was recorded. Additionally, it could be used as a chicken lice repellent, herbicide, and natural insecticide against mosquito larvae and natural molluscicide. In veterinary medicine, can be used as an anthelmintic against the eggs and larvae of bovine strongyles parasites, and as an antibiotic against bovine mastitis caused by resistant bacterial strains. Due to the mentioned benefits, there is a tendency for the cultivation of in order to ensure high-quality raw material, but more firm scientific evidence and well-designed clinical trials are necessary for the well-established use of herb and its preparations.
是一种具有高生物活性潜力的植物。它含有 marrubiin，这是该属特有的一种 labdane 二萜，以及复杂的酚类化合物混合物。根据众多研究，具有良好的抗氧化剂作用，因此，它可能在癌症、糖尿病和肝脏疾病的治疗中具有潜在的应用价值。此外，还讨论了其抗炎、愈合伤口、降血压、降血脂和镇静作用。除此之外，它还具有抗菌活性，特别是对革兰氏阳性菌、真菌、单纯疱疹病毒和寄生虫如 、 、 具有抑制作用。此外，它可用作鸡虱驱避剂、除草剂和天然杀虫剂，以防治蚊幼虫和天然软体动物杀虫剂。在兽医领域，可用作驱虫药来驱除牛的 Strongyles 寄生虫的卵和幼虫，以及抗生素来治疗由耐药菌引起的牛乳腺炎。由于这些益处，存在种植 的趋势，以确保高质量的原料，但需要更坚实的科学证据和精心设计的临床试验，以便为 使用 和其制剂提供良好的依据。
