Rustgi A K, Peppercorn M A
Department of Medicine, Beth Israel Hospital, Boston, MA.
Arch Intern Med. 1988 Jul;148(7):1583-4.
A patient with systemic lupus erythematosus developed gluten-sensitive enteropathy, or celiac sprue. The patient's histocompatibility antigens included HLA-B8 and HLA-DR3, previously found to have a high frequency in gluten-sensitive enteropathy and possibility increased as well in systemic lupus erythematosus. Such histocompatibility antigens are common to a variety of autoimmune disorders. An immune basis for the association is discussed herein.
一名系统性红斑狼疮患者出现了麸质敏感性肠病，即乳糜泻。该患者的组织相容性抗原包括HLA - B8和HLA - DR3，此前发现这些抗原在麸质敏感性肠病中出现频率较高，在系统性红斑狼疮中出现的可能性也有所增加。此类组织相容性抗原在多种自身免疫性疾病中较为常见。本文讨论了这种关联的免疫基础。
