人类非洲锥虫病：采用脑脊液双重离心法检测锥虫
Human African trypanosomiasis: use of double centrifugation of cerebrospinal fluid to detect trypanosomes.
作者信息
Cattand P, Miezan B T, de Raadt P
出版信息
Bull World Health Organ. 1988;66(1):83-6.
Abstract
A double-centrifugation technique for the detection of trypanosomes in samples of cerebrospinal fluid is described and evaluated. The results of the analysis of samples of cerebrospinal fluid from 128 patients with Trypanosoma brucei gambiense sleeping sickness from the Daloa area of Côte d'Ivoire, obtained using single centrifugation, are compared with those obtained using the new method. Double centrifugation is at least twice as sensitive as single centrifugation and results in an increase of 37% in the early detection of late-stage case of the disease. The technique is easily implemented under field conditions.
摘要
本文描述并评估了一种用于检测脑脊液样本中锥虫的双重离心技术。将使用单重离心法从科特迪瓦大洛阿地区128例布氏冈比亚锥虫昏睡病患者的脑脊液样本分析结果，与使用新方法获得的结果进行比较。双重离心的灵敏度至少是单重离心的两倍，并且在该疾病晚期病例的早期检测中，检测率提高了37%。该技术在现场条件下易于实施。
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