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本文引用的文献

1
Left Atrial Mass Invasion from Pulmonary Neoplasm Extension via the Right Upper Pulmonary Vein Presenting as Ipsilateral Stroke.肺肿瘤经右上肺静脉蔓延致左心房肿物侵犯并表现为同侧脑卒中
Case Rep Med. 2016;2016:7084234. doi: 10.1155/2016/7084234. Epub 2016 Dec 8.
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Left atrial extension of lung carcinoma simulating myocardial infarction, unusual presentation: case report and literature review.模拟心肌梗死的肺癌左心房浸润,罕见表现:病例报告及文献复习
Tanaffos. 2011;10(2):69-71.
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Surgical results and long-term follow-up of T(4)-non-small cell lung cancer invading the left atrium or the intrapericardial base of the pulmonary veins.侵犯左心房或肺静脉心包内基部的T(4)期非小细胞肺癌的手术结果及长期随访
Interact Cardiovasc Thorac Surg. 2012 Apr;14(4):415-9. doi: 10.1093/icvts/ivr160. Epub 2012 Jan 22.
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Lung cancer invading the pericardium: quantum of lymph nodes.肺癌侵犯心包:淋巴结转移情况。
Ann Thorac Surg. 2010 Dec;90(6):1773-7. doi: 10.1016/j.athoracsur.2010.07.039.
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Giant intracardiac neoplasic thrombus of a large cell neuroendocrine carcinoma of the lung.肺大细胞神经内分泌癌巨大心内赘生物性血栓。
Cardiovasc Pathol. 2010 May-Jun;19(3):e85-7. doi: 10.1016/j.carpath.2008.10.010. Epub 2009 Jan 14.
6
Lung cancer mimicking left atrial mass.酷似左心房肿块的肺癌
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Intravenous extension of sarcomatoid carcinoma of the lung to the left atrium.
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Posterior mediastinal spread of bronchogenic carcinoma simulating a mass within the left atrium.
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10
Extension of bronchogenic carcinoma through pulmonary vein into the left atrium detected by echocardiography.经超声心动图检测到支气管源性癌经肺静脉延伸至左心房。
Echocardiography. 2004 Feb;21(2):189-91. doi: 10.1111/j.0742-2822.2004.02178.x.

一例经肺静脉延伸至左心房的肺癌报告。

Report of a lung carcinoma extended to the left atrium through pulmonary vein.

作者信息

Cipriano Federico, Dessoti Lycio U, Rodrigues Alfredo José, Vicente Walter Vilella de Andrade, Chahud Fernando, Evora Paulo Roberto B

机构信息

Department of Surgery and Anatomy, Ribeirão Preto School of Medicine, University of São Paulo, Ribeirão Preto, SP, Brazil.

Department of Pathology, Ribeirão Preto School of Medicine, University of São Paulo, Ribeirão Preto, SP, Brazil.

出版信息

J Thorac Dis. 2018 Jan;10(1):E46-E51. doi: 10.21037/jtd.2017.12.33.

DOI:10.21037/jtd.2017.12.33
PMID:29600103
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5863176/
Abstract

Lung cancers may extend along or grow through the pulmonary veins to invade or lie within the left atrium (LA). A 62-year-old man, previously healthy, presented with 1-month ventilatory-independent right hemithorax back pain, dry cough and large effort dyspnea. He also referred weight loss of 12 kg in 10 months and denied hemoptysis. As antecedents, he smoked for 40 years and moderate daily alcoholism. On physical examination, the patient was in good general condition, hydrated and regular respiration at rest [blood pressure (BP) =120/80 mmHg; heart rate (HR) =90 bpm; respiratory rate (RR) =16 rpm]. Cardiac auscultation revealed two standard rhythmic sounds without murmurs. Pulmonary auscultation revealed a slightly diminished vesicular murmur in the lower 1/3 of the right hemithorax without adventitious noises. Chest radiography showed a mass over the right lower lung. A CT scan confirmed the radiography image with the mass extending along the right inferior pulmonary vein and a tumor in the LA. Transthoracic and transesophageal echocardiography revealed large mass within the LA (occupying almost the entire cavity), measuring about 10 cm × 3 cm at its largest diameter, prolapsing into the left ventricle. Bronchoscopy, head CT scan, and whole-body bone scintigraphy investigation did not show any distant metastasis. The patient was successfully operated removing the intracardiac and inferior pulmonary vein tumor with the aid of cardiopulmonary bypass, followed by a right inferior lobectomy carried out after 25 days. After 30 days from surgery presented seizures associated a brain metastasis evidenced by CT when adjuvant radio and chemotherapy was started. During the next 90 days, the clinical conditions worsened, and the patient died 4 months after the surgical treatment. The case report has two primary justifications, even considering the poor outcome: (I) rarity and (II) the possibility of the surgical treatment.

摘要

肺癌可能沿肺静脉延伸或穿过肺静脉侵犯左心房(LA)或位于左心房内。一名62岁男性,既往健康,出现1个月与通气无关的右半胸背痛、干咳和劳力性呼吸困难。他还自述10个月内体重减轻12kg,否认咯血。既往史方面,他吸烟40年,有中度每日饮酒史。体格检查时,患者一般情况良好,无脱水,静息呼吸规律[血压(BP)=120/80mmHg;心率(HR)=90次/分;呼吸频率(RR)=16次/分]。心脏听诊闻及两个标准节律音,无杂音。肺部听诊发现右半胸下1/3处肺泡呼吸音略减弱,无附加音。胸部X线显示右下肺有一肿块。CT扫描证实了X线影像,肿块沿右下肺静脉延伸,左心房有一肿瘤。经胸和经食管超声心动图显示左心房内有一巨大肿块(几乎占据整个腔室),最大直径约10cm×3cm,突入左心室。支气管镜检查、头部CT扫描和全身骨闪烁显像检查未显示任何远处转移。患者在体外循环辅助下成功手术切除心内及右下肺静脉肿瘤,25天后进行了右下肺叶切除术。术后30天出现癫痫发作,CT显示有脑转移,随后开始辅助放疗和化疗。在接下来的90天里,临床情况恶化,患者在手术治疗4个月后死亡。即使考虑到预后不佳,该病例报告仍有两个主要理由:(I)罕见性和(II)手术治疗的可能性。