Barnawi Ashwaq I, Kordy Faisal N, Almuwallad Ohoud K, Kassarah Khloud A
Department of Pediatrics, Madina Maternity & Children's Hospital, Al-Madina Al-Munawara, Kingdom of Saudi Arabia. E-mail.
Saudi Med J. 2020 Jul;41(7):753-756. doi: 10.15537/smj.2020.7.25720.
Elizabethkingia meningoseptica (E. meningoseptica ) are Gram-negative bacteria commonly associated with nosocomial infections in neonates. This is a case study of E. meningoseptica, presented as meningitis and sepsis in a term baby. The female infant was born by vaginal delivery at 37 weeks gestational age. The case was peculiar because the baby was neither premature nor immuno-compromised, which are known risk factors for E. meningoseptica infection. The onset began on the second day of the neonate's life. On day 3, peripheral blood culture and cerebrospinal fluid findings isolated a gram-negative bacteria identified as E. meningoseptica. The first-line antibiotics therapy was changed to ciprofloxacin, vancomycin, and rifampicin, based on the laboratory determination of antimicrobial sensitivity. The patient's clinical condition improved, although post hemorrhagic ventricular dilatation was revealed by imaging studies. Clinicians should possess proper awareness of the antibiotic sensitivity of E. meningoseptica, as it is important in preventing high rates of morbidity and mortality.
脑膜败血伊丽莎白金菌（E. meningoseptica）是革兰氏阴性菌，通常与新生儿医院感染有关。这是一例脑膜败血伊丽莎白金菌的病例研究，该菌在一名足月儿中表现为脑膜炎和败血症。这名女婴在孕37周时经阴道分娩出生。该病例很特殊，因为婴儿既不是早产儿也没有免疫功能低下，而这两种情况是已知的脑膜败血伊丽莎白金菌感染的危险因素。发病始于新生儿出生后的第二天。在第3天，外周血培养和脑脊液检查结果分离出一种革兰氏阴性菌，鉴定为脑膜败血伊丽莎白金菌。根据实验室对抗菌药物敏感性的测定，一线抗生素治疗改为环丙沙星、万古霉素和利福平。尽管影像学检查显示有出血后脑室扩张，但患者的临床状况有所改善。临床医生应正确认识脑膜败血伊丽莎白金菌的抗生素敏感性，因为这对于预防高发病率和死亡率很重要。
