Alhaj Sulaiman Abdallah, Bakleh Mouayad Zuheir, Ali Reem, Aouida Mustapha, Ramotar Dindial
Division of Biological and Biomedical Sciences, College of Health and Life Sciences, Hamad Bin Khalifa University, Education City, Qatar Foundation, P.O. Box 34110, Doha, Qatar.
Translational Oncology Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation (QF), P.O. Box 34110, Doha, Qatar.
BMC Infect Dis. 2025 Aug 21;25(1):1052. doi: 10.1186/s12879-025-11420-5.
Elizabethkingia is a family of bacteria present in the environment causing infections that have emerged as a significant clinical concern in the Middle East and North Africa region. Despite sporadic reports and case studies, the epidemiology of Elizabethkingia-encompassing its prevalence, antimicrobial resistance profiles, and clinical outcomes-remains largely anecdotal and fragmented. In this review, we systematically screened and analyzed the published literature to provide a comprehensive assessment of the distribution, antibiotic resistance characteristics, and clinical features of Elizabethkingia infections in different samples across the region. Our analysis consolidates existing evidence to highlight the true burden of Elizabethkingia and the emergence of multidrug-resistant strains. By identifying current gaps in data and standardization, this review aims to inform and engage clinicians, microbiologists, epidemiologists, and public health stakeholders in developing coordinated strategies to monitor, prevent, and manage these infections within a One Health framework.
伊丽莎白菌属是一类存在于环境中的细菌，可引发感染，已成为中东和北非地区一个重大的临床关注点。尽管有零星的报告和病例研究，但关于伊丽莎白菌属的流行病学——包括其流行情况、抗菌药物耐药谱以及临床结局——在很大程度上仍只是传闻且支离破碎。在本综述中，我们系统地筛选和分析了已发表的文献，以全面评估该地区不同样本中伊丽莎白菌属感染的分布、抗生素耐药特征及临床特征。我们的分析整合了现有证据，以突出伊丽莎白菌属的真实负担以及多重耐药菌株的出现。通过识别当前数据和标准化方面的差距，本综述旨在为临床医生、微生物学家、流行病学家和公共卫生利益相关者提供信息，并促使他们参与制定协调战略，以便在“同一健康”框架内监测、预防和管理这些感染。
