Noda Keisuke, Kuroki Tamotsu, Yamashita Mampei, Hirayama Takanori, Natsuda Koji, Kobayashi Shinichiro, Tokunaga Takayuki, Yamanouchi Kosho, Takeshita Hiroaki, Miura Shiro, Maeda Shigeto
Department of Surgery, National Hospital Organization Nagasaki Medical Center, 2-1001-1, Kubara, Omura City, Nagasaki, 856-8562, Japan.
Department of Pathology, National Hospital Organization Nagasaki Medical Center, Omura, Japan.
Surg Case Rep. 2020 Jun 29;6(1):154. doi: 10.1186/s40792-020-00918-6.
Pancreatic neuroendocrine tumors (PNETs) are typically solid neoplasms but, in very rare cases, present as cystic lesions. We describe a case of a cystic neuroendocrine tumor that developed as a small cystic lesion.
In 2011, a 66-year-old Japanese woman underwent computed tomography (CT) that revealed a cystic lesion in the tail of the pancreas measuring 9 mm. She did not have any symptoms. She underwent a CT scan every year thereafter. The cystic lesion gradually increased and was 40 mm in 2019; endoscopic retrograde pancreatography (ERP) was then performed. Cytological examination demonstrated class IIIb adenocarcinoma, and we conducted laparoscopic distal pancreatectomy. Pathological examination showed PNET.
Although cystic change of PNET is generally caused by ischemia or necrosis inside the tumor, in our case, PNET occurred as a small cyst that increased without changing form.
胰腺神经内分泌肿瘤(PNETs)通常为实性肿瘤,但在极少数情况下表现为囊性病变。我们描述了一例以小囊性病变形式出现的囊性神经内分泌肿瘤病例。
2011年,一名66岁的日本女性接受计算机断层扫描(CT)检查,发现胰腺尾部有一个9毫米的囊性病变。她没有任何症状。此后每年进行一次CT扫描。囊性病变逐渐增大,2019年时为40毫米;随后进行了内镜逆行胰胆管造影(ERP)。细胞学检查显示为IIIb级腺癌,于是我们进行了腹腔镜远端胰腺切除术。病理检查显示为PNET。
虽然PNET的囊性改变通常是由肿瘤内部的缺血或坏死引起的,但在我们的病例中,PNET是以一个小囊肿的形式出现的,且囊肿在未改变形态的情况下增大。